PAV-0056

PAV-0056

Clinical data
Drug class	Painkiller; bradykinin receptor B1 antagonist
Identifiers
IUPAC name Methyl 2-(7-nitro-2-oxo-5-phenyl-3-propoxy-2,3-dihydro-1H-benzo[e][1,4]diazepin-1-yl)acetate
CAS Number	2340236-61-3
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C21H21N3O6
Molar mass	411.414 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCCOC1C(=O)N(C2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3)CC(=O)OC
InChI InChI=1S/C21H21N3O6/c1-3-11-30-20-21(26)23(13-18(25)29-2)17-10-9-15(24(27)28)12-16(17)19(22-20)14-7-5-4-6-8-14/h4-10,12,20H,3,11,13H2,1-2H3 Key:HMRUZCRGFQGPLA-UHFFFAOYSA-N

PAV-0056 is a novel benzodiazepine-based analgesic currently under development in Russia. As of at least 2024, it remains in the investigational stage. This experimental, non-opioid analgesic is a potential next-generation drug derived from 1,4-benzodiazepin-2-one, acting as a selective bradykinin receptor B1 antagonist.

References

Template:Benzodiazepines

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