REPAIR Impact Fund
| File:Repair-impact-fund-logo.png | |
| Investment Fund | |
| ISIN | 🆔 |
| Industry | Life Sciences Anti-Microbial Resistance (AMR) |
| Founded 📆 | 2018 |
| Founder 👔 | Novo Holdings A/S |
| Headquarters 🏙️ | , , |
Area served 🗺️ | |
| Services | Investments in Life Sciences |
| Total assets | $165 million |
| Members | |
Number of employees | |
| 🌐 Website | www.repair-impact-fund.com |
| 📇 Address | |
| 📞 telephone | |
The Repair Impact Fund is an investment fund established in 2018[1] and operated by Novo Holdings A/S.[2] The fund is backed by $165 million[3] by Novo Holdings A/S equivalent of around £119 million[4] and €135 million[5][6][7]. The fund is aiming at investing $20-40 million[1] a year over a three to five-year period[1].
The fund invests into European and US start-ups, early-stage ventures and corporate spin-outs or projects, focusing on developing innovative solutions regarding anti-fungals and antibiotics, aimed against anti-microbial resistance (AMR)[5][6], also commonly referred to as antibiotics-resistance, which the World Health Organization regards as the greatest threat to human health[1].
Purpose: Fighting anti-microbial resistance
The main purpose of the REPAIR Impact Fund is to invest in new companies, initiatives and methods as part of finding solutions to the growing threat from anti-microbial resistance, or so-called "super-bugs". The REPAIR Impact Fund specialises in investing in life-science companies focusing on developing therapies and solutions to combat anti-microbial resistance[2]. The fund focuses on initiatives that target the 12 drug-resistant families of bacteria[6][2], the so-called antibiotic-resistant "priority pathogens"[6][7] which is defined by the World Health Organization (WHO) as "bacteria for which new antibiotics are urgently needed".[7]
Anti-microbial resistance: A growing threat to mankind
Anti-microbial resistance, and the rise of drug-resistant bacteria, is a growing threat to modern medicine and to the health of the human population. The emergence of infections resistant to even last-resort-antibiotics has been made worse in recent years due to the overuse of antibiotics worldwide and the lack of cutbacks in drug research combined with lack of financial interest in developing new antibiotics.
According to current statistics, over 700,000[1] people die annually from antibiotics-resistant infections, and the number appears to be climbing[6] at such a rate that it is projected that antibiotic-resistant infections will cause more deaths than cancer by the year 2050.[8][9]
Name, origin and investment focus
The name (REPAIR Impact Fund) is an abbreviation of "Replenishing and Enabling the Pipeline for Anti-Infective Resistance".[6][5] The REPAIR Impact Fund has been backed with $165 million[3] to invest in approximately 20 companies[5] throughout a five-year period in the struggle to combat the increasing threat from antibiotics-resistance. Investment focus of the REPAIR Impact Fund is primarily within the life-sciences and is primarily focused on projects in Europe and the United States.
Investments
- 2018: MinervaX: Danish biotech company developing vaccines against Group B Streptococci (GBS). Investment: $4.1 million (€3.6 million).[8]
- 2018: Polyphor: Swiss biotech company focusing on developing new types of antibiotics.[8] Investment: $11.5 million (CHF 11.5 million).[10]
- 2018: Entasis Therapeutics (NASDAQ: ETTX): Boston-based biotech company which develops new kinds of inhibitors targeting multiresistant infections within the group "Pseudomonas Aeruginosa strains". Investment: $10 million.[8]
- 2018: Procarta Biosystems: UK-based biotech company focusing on the development of treatments for complicated urinary tract infections and intra-abdominal infections. Investment: $1.7 million (€1.5 million).[8]
Administration and management
Key executives for Novo REPAIR Impact Fund:[2]
- Mr. Aleks Engel, PhD - Director [2]
- Mrs. Emmanuelle Coutanceau, Ph.D - Partner [2]
- Mr. Søren Møller, PhD - Managing Partner Novo Seeds[2]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Financial Times (ft.com): Novo to invest $165m in first ‘superbug’ venture fund. https://www.ft.com/content/30d1d2a4-1bb3-11e8-aaca-4574d7dabfb6
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Bloomberg.com: REPAIR Impact Fund company information: https://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=556951089
- ↑ 3.0 3.1 Biospace.com - Novo Nordisk Investment Fund Backs Companies Developing Therapies Combatting Antimicrobial Resistance: https://www.biospace.com/article/novo-nordisk-investment-fund-backs-companies-developing-therapies-combatting-antimicrobial-resistance/
- ↑ Hirschler, Ben (Feb 28, 2018). "Novo Holdings launches $165 million 'superbug' drug venture fund". Reuters. Retrieved Feb 1, 2019.
- ↑ 5.0 5.1 5.2 5.3 Combacte.com: Novo Holdings Launches €135m Fund to Combat Antimicrobial Resistance: https://www.combacte.com/news/novo-holdings-launches-e135m-fund-combat-antimicrobial-resistance/
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 European Biotechnology - Life Science and Industry Magazine: Novo Holdings launches €135m fund to combat antimicrobial resistance. https://european-biotechnology.com/up-to-date/latest-news/news/novo-holdings-launches-eur135m-fund-to-combat-antimicrobial-resistance.html
- ↑ 7.0 7.1 7.2 World Health Organization (WHO.com): "WHO publishes list of bacteria for which new antibiotics are urgently needed" https://www.who.int/news-room/detail/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed
- ↑ 8.0 8.1 8.2 8.3 8.4 Impactalpha.com: Novo’s REPAIR Impact Fund backs three companies tackling antibiotic resistance. https://impactalpha.com/novos-repair-impact-fund-backs-three-companies-tackling-antibiotic-resistance/
- ↑ The Week: UK supermarkets 'contributing to antibiotics crisis': https://www.theweek.co.uk/antibiotics/51908/antibiotics-resistance-could-cause-10m-deaths-a-year-by-2050
- ↑ Biocentury.com: NOVO'S REPAIR FUND MAKES FIRST INVESTMENT IN SWISS ANTIBIOTIC COMPANY https://www.biocentury.com/bc-week-review/financial-news/completed-offerings/2018-09-07/novos-repair-fund-makes-first-
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