Raffaele A. Calogero
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Prof. Raffaele A. Calogero is an Associate Professor at the University of Torino in the department of Molecular Biology and Health Science.[1] He is also the President of the Italian Bioinformatics Society.[2]
Education[edit]
Prof. Calogero received his graduation in Biological sciences from the Naples University in Italy, followed by his post-degree training at Institute of Genetics in the department of General and Molecular Biology from the same university. He received a fellowship from the Max Planck Institute for Molecular Genetics, Berlin, Germany.[3][4]
Research and career[edit]
Prof. Calogero research interests include the development and optimization of analysis workflows and in mining transcription-based experiments, mainly in the oncology framework, and Single cell omics. His research on Microvesicles Derived from Mesenchymal Stem Cells[5] Protect Against Acute Tubular Injury revealed that the mRNA transfer from MSCs to target cells via MV internalisation contributes to the regenerative function of MSCs, together with soluble factors, and may be utilised as a potential therapeutic method for regenerative medicine.[6][7][8][9][10][11] He also conducted research on the Microvesicles produced from endothelial progenitor cells induce an angiogenic response in endothelial cells via a horizontal transfer of mRNA.[12]
Prof. Raffaele A. Calogero was a researcher at SORIN Biomedica S.p.A. Later, he was appointed as an Associate Professor of Molecular Biology at the University of Naples (Italy) in 1992 and went to the University of Turin in 1998.
Patents[edit]
Prof. Raffaele A. Calogero obtained many patents for his inventions and his patents include
- Process to purify proteins from cell systems (EP0571337B1)[13]
- Recombinant hepatitis delta antigen, process for the purification and use thereof (EP0485347A3)[14]
- Procedure for the purification of proteins from cell systems (ITRM920385A1)[15]
- Nucleic acid molecules encoding for chimeric cspg4 proteins and therapeutic uses thereof (US20190008940A1)[16]
- Sequences that induce / stimulate the start of translation and their use (ITMI982733A1)
- Building of nucleic acid, vector and DNA vaccine including the same manufactured (ITTO20100028A1).
Publications[edit]
- Raffaele A Calogero, Cynthia L Pon, Maria A Canonaco, Claudio O Gualerzi. "Selection of the mRNA translation initiation region by Escherichia coli ribosomes". Proceedings of the National Academy of Sciences.[17]
- Raffaele A Calogero, Cynthia L Pon, Claudio O Gualerzi. "Chemical synthesis and in vivo hyperexpression of a modular gene coding for Escherichia coli translational initiation factor IF1". Molecular and General Genetics MGG.[18]
- Federica Cavallo, Guido Forni,. " Are oncoantigens suitable targets for anti-tumour therapy? ". Nature Review Cancer.[19]
- Beccuti M, Cordero F, Arigoni M, Panero R, Amparore EG, Donatelli S, Calogero RA. "SeqBox: RNAseq/ChIPseq reproducible analysis on a consumer game computer". Bioinformatics.[20]
- Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD. " Live-animal imaging of native haematopoietic stem and progenitor cells". Nature.[21]
External links[edit]
Raffaele A Calogero on Google scholar
References[edit]
- ↑ "Raffaele Calogero". Spatial Biology US: In-Person. Retrieved 2022-01-12.
- ↑ Binaria, Res. "Steering Committee". B.IT.S. Bioinformatics Italian Society. Retrieved 2022-01-12.
- ↑ "CALOGERO Raffaele Adolfo". Università di Torino (in italiano). Retrieved 2022-01-12.
- ↑ "Raffaele Calogero". Spatial Biology US: In-Person. Retrieved 2022-01-12.
- ↑ Bruno, Stefania; Grange, Cristina; Deregibus, Maria Chiara; Calogero, Raffaele A.; Saviozzi, Silvia; Collino, Federica; Morando, Laura; Busca, Alessandro; Falda, Michele; Bussolati, Benedetta; Tetta, Ciro (2009-05-01). "Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury". Journal of the American Society of Nephrology. 20 (5): 1053–1067. doi:10.1681/ASN.2008070798. ISSN 1046-6673. PMC 2676194. PMID 19389847.CS1 maint: PMC format (link)
- ↑ Deregibus, Maria Chiara; Cantaluppi, Vincenzo; Calogero, Raffaele; Lo Iacono, Marco; Tetta, Ciro; Biancone, Luigi; Bruno, Stefania; Bussolati, Benedetta; Camussi, Giovanni (2007-10-01). "Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA". Blood. 110 (7): 2440–2448. doi:10.1182/blood-2007-03-078709. ISSN 0006-4971. PMID 17536014.
- ↑ Adamo, Annalisa; Brandi, Jessica; Caligola, Simone; Delfino, Pietro; Bazzoni, Riccardo; Carusone, Roberta; Cecconi, Daniela; Giugno, Rosalba; Manfredi, Marcello; Robotti, Elisa; Marengo, Emilio (2019-03-12). "Extracellular Vesicles Mediate Mesenchymal Stromal Cell-Dependent Regulation of B Cell PI3K-AKT Signaling Pathway and Actin Cytoskeleton". Frontiers in Immunology. 10: 446. doi:10.3389/fimmu.2019.00446. ISSN 1664-3224. PMC 6423067. PMID 30915084.
- ↑ Adamo, Annalisa; Brandi, Jessica; Caligola, Simone; Delfino, Pietro; Bazzoni, Riccardo; Carusone, Roberta; Cecconi, Daniela; Giugno, Rosalba; Manfredi, Marcello; Robotti, Elisa; Marengo, Emilio (2019). "Extracellular Vesicles Mediate Mesenchymal Stromal Cell-Dependent Regulation of B Cell PI3K-AKT Signaling Pathway and Actin Cytoskeleton". Frontiers in Immunology. 10: 446. doi:10.3389/fimmu.2019.00446. ISSN 1664-3224. PMC 6423067. PMID 30915084.CS1 maint: PMC format (link)
- ↑ Deregibus, Maria Chiara; Cantaluppi, Vincenzo; Calogero, Raffaele; Lo Iacono, Marco; Tetta, Ciro; Biancone, Luigi; Bruno, Stefania; Bussolati, Benedetta; Camussi, Giovanni (2007-10-01). "Endothelial progenitor cell–derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA". Blood. 110 (7): 2440–2448. doi:10.1182/blood-2007-03-078709. ISSN 0006-4971.
- ↑ Deregibus, Maria Chiara; Cantaluppi, Vincenzo; Calogero, Raffaele; Lo Iacono, Marco; Tetta, Ciro; Biancone, Luigi; Bruno, Stefania; Bussolati, Benedetta; Camussi, Giovanni (2007-10-01). "Endothelial progenitor cell–derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA". Blood. 110 (7): 2440–2448. doi:10.1182/blood-2007-03-078709. ISSN 0006-4971.
- ↑ Ciccocioppo, Rachele; Santos, Claudia C. Dos; Baumgart, Daniel C.; Cangemi, Giuseppina C.; Cardinale, Vincenzo; Ciacci, Carolina; Coppi, Paolo De; Haldar, Debashis; Klersy, Catherine; Nostro, M. Cristina; Ott, Michael (2018-03-01). "Proceedings of the signature series event of the international society for cellular therapy: "Advancements in cellular therapies and regenerative medicine in digestive diseases," London, United Kingdom, May 3, 2017". Cytotherapy. 20 (3): 461–476. doi:10.1016/j.jcyt.2017.12.004. ISSN 1465-3249. PMID 29398624.
- ↑ Deregibus, Maria Chiara; Cantaluppi, Vincenzo; Calogero, Raffaele; Lo Iacono, Marco; Tetta, Ciro; Biancone, Luigi; Bruno, Stefania; Bussolati, Benedetta; Camussi, Giovanni (2007-10-01). "Endothelial progenitor cell–derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA". Blood. 110 (7): 2440–2448. doi:10.1182/blood-2007-03-078709. ISSN 0006-4971.
- ↑ EP0571337B1, Bonelli, Fabrizio; Elvi Cecconato & Raffaele Calogero, "Process to purify proteins from cell systems", issued 1999-06-30
- ↑ EP0485347A3, Bonelli, Fabrizio; Raffaele Calogero & Antonio Boniolo, "Recombinant hepatitis delta antigen, process for the purification and use thereof", issued 1992-07-29
- ↑ EP0571337B1, Bonelli, Fabrizio; Elvi Cecconato & Raffaele Calogero, "Process to purify proteins from cell systems", issued 1999-06-30
- ↑ US20190008940A1, Cavallo, Federica; Paolo BURACCO & Federica RICCARDO et al., "Nucleic acid molecules encoding for chimeric cspg4 proteins and therapeutic uses thereof", issued 2019-01-10
- ↑ Calogero, R. A.; Pon, C. L.; Canonaco, M. A.; Gualerzi, C. O. (1988-09-01). "Selection of the mRNA translation initiation region by Escherichia coli ribosomes". Proceedings of the National Academy of Sciences. 85 (17): 6427–6431. doi:10.1073/pnas.85.17.6427. ISSN 0027-8424. PMC 281985. PMID 3045816.CS1 maint: PMC format (link)
- ↑ Calogero, Raffaele A.; Pon, Cynthia L.; Gualerzi, Claudio O. (1987-06-01). "Chemical synthesis and in vivo hyperexpression of a modular gene coding for Escherichia coli translational initiation factor IF1". Molecular and General Genetics MGG. 208 (1): 63–69. doi:10.1007/BF00330423. ISSN 1432-1874.
- ↑ Cavallo, Federica; Calogero, Raffaele Adolfo; Forni, Guido (2007-09). "Are oncoantigens suitable targets for anti-tumour therapy?". Nature Reviews Cancer. 7 (9): 707–713. doi:10.1038/nrc2208. ISSN 1474-1768. Check date values in:
|date=(help) - ↑ Beccuti, Marco; Cordero, Francesca; Arigoni, Maddalena; Panero, Riccardo; Amparore, Elvio G; Donatelli, Susanna; Calogero, Raffaele A (2018-03-01). "SeqBox: RNAseq/ChIPseq reproducible analysis on a consumer game computer". Bioinformatics. 34 (5): 871–872. doi:10.1093/bioinformatics/btx674. ISSN 1367-4803. PMC 6030956. PMID 29069297.CS1 maint: PMC format (link)
- ↑ Christodoulou, Constantina; Spencer, Joel A.; Yeh, Shu-Chi A.; Turcotte, Raphaël; Kokkaliaris, Konstantinos D.; Panero, Riccardo; Ramos, Azucena; Guo, Guoji; Seyedhassantehrani, Negar; Esipova, Tatiana V.; Vinogradov, Sergei A. (2020-02). "Live-animal imaging of native haematopoietic stem and progenitor cells". Nature. 578 (7794): 278–283. doi:10.1038/s41586-020-1971-z. ISSN 1476-4687. PMC PMC7021587 Check
|pmc=value (help). PMID 32025033 Check|pmid=value (help). Check date values in:|date=(help)CS1 maint: PMC format (link)
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