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Scott D. Tanner

From EverybodyWiki Bios & Wiki



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Scott D. Tanner Scientist

Scott D. Tanner

Scott Tanner is a Canadian scientist, innovator[1], inventor [2] [3] and entrepreneur.[4] His areas of expertise include mass spectroscopy, especially inductively coupled plasma mass spectrometry (ICP-MS), and mass cytometry.

Scott is best known for his work on the fundamentals of Inductively Coupled Plasma Mass Spectrometry,[5] for the invention of mass cytometry,[6] and co-founding (with Dmitry Bandura, Vladimir Baranov and Olga Ornatsky) DVS Sciences [4] in 2004,(acquired by Fluidigm in 2014 and then renamed to Standard BioTools in 2022[7]) the company that first commercialized the instrument and reagents of mass cytometry.


Mass Cytometry is a transformative technology that is instrumental in driving groundbreaking discoveries in immunology, cancer, stem cell research, neurology and many more biological areas by enabling researchers to deeply profile protein biomarkers from cells and tissues at single-cell resolution” (source: Dr. Robert Moritz, Vice President, Human Proteome Organization).[8]

Early Life and Education[edit]

Scott was born and raised in St. Catharines, Ontario Canada. He bought his first chemistry set, from his brother, at age 6.[9] [10] Through his early teenage years, he was provided with laboratory space at Brock University, under the guidance of Dr. E.A. Cherniak and Dr. F.P. Koffyberg, where he attempted to replicate Geiger–Marsden experiments also known as Rutherford’s experiment (scattering of alpha particles by gold foil) using various home-built instruments, including cloud chambers.[9] [10]

Scott graduated with a BSC in Chemistry from York University in 1976. During his undergraduate years, he became a nationally ranked gymnast. [9] [10] [11]An injury at the Olympic trials ended his competitive gymnastics career, and he took up marathon running during graduate school (best time 2:47:13).[9] [10] He received a Doctor of Philosophy (Chemistry) from York University in 1980, having studied ion-molecule reaction kinetics and flame ion chemistry with Drs. D.K Bohme and J.M. Goodings.[9] [10]

Biography[edit]

Dr. Tanner joined SCIEX, which later became MDS SCIEX, in 1980 as a research scientist. He became Principal Scientist in 2000. In his 25 years at SCIEX, Dr. Tanner developed and helped to commercialize a string of Mass Spectrometry products.

Scott published over 74 peer-reviewed scientific articles, and holds 22 US patents[12] (with corresponding filings in other countries), including 13 patents on Mass Cytometry technology

Scott was a co-founder of DVS Sciences and, as the President and CEO, saw the company through the development and commercial launch of its first products.

The products that DVS Sciences brought to the global market were originally developed at the University of Toronto where Dr. Tanner was a Professor in the Institute of Biomaterials and Biomedical Engineering and then in Chemistry.

Career[edit]

  • Principal Scientist SCIEX - 1980-2005[9]
  • Associate Professor (CLTA) at the University of Toronto, first in the Institute of Biomaterials and Biomedical Engineering (2005-2008) and then in Chemistry 2008-2013.
  • Adjunct Professor at York University in the Department of Chemistry 2015-2018

Books[edit]

  • 2003 - Plasma Source Mass Spectrometry: Applications and Emerging Technologies
    ISBN 10: 0854046038 / ISBN 13: 9780854046034 [14]
  • 2001 - Plasma Source Mass Spectrometry: The New Millennium
    ISBN-10: ‎0854048952 / ISBN-13‏: ‎978-0854048953 [15]
  • 1999 - Plasma Source Mass Spectrometry: New Developments and Applications
    ISBN-10: 0854047492 / ISBN-13: 978-0854047499 [16]
  • 1997 - Plasma Source Mass Spectrometry: Developments and Applications
    ISBN 10: 0854047271 ISBN / 13: 9780854047277 [17]

Research[edit]

  • Detection of TCDD (dioxin) in soil and water[18], explosives [19], chemical agents.[20]
  • Development of the ELAN 6000 ICP-MS [21]

Awards and honors[edit]

  • 2020 Lifetime Achievement Award in Plasma Spectrochemistry[26]
  • 2001 Manning Innovation Award, Award of Distinction[1] Dr. Scott Tanner, together with Dr. Vladimir Baranov, received the Manning Award of Distinction from the Manning Innovation Awards Foundation for the remarkable invention of the ICP-MS Dynamic Reaction Cell (Collision/reaction cell).[32]

Publications[edit]

Scott has published more than 75 peer-reviewed articles.
The 13 most cited (more than 200 citations each) include:

  • May 2011 - Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum[36] (2218 citations as of Jan 11 2023)
  • Sept 2010 - Highly Multiparametric Analysis by Mass Cytometry[37] (398 citations as of Jan 11 2023)
  • Aug 2009 - Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry[38] (1148 citations as of Jan 11 2023)
  • Sept 2002 - Reaction Cells and Collision Cells for ICP-MS: A Tutorial Review[39] (821 citations as of Jan 11 2023)
  • April 2002 - A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection[40] (238 citations as of Jan 11 2023)
  • April 2002 - Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell[41] (221 citations as of Jan 11 2023)
  • July 2001 - Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS[42] (202 citations as of Jan 11 2023)
  • Aug 2000 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III.[43] (245 citations as of Jan 11 2023)
  • Nov 1999 - A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Pproduced within the Cell[44] (212 citations as of Jan 11 2023)
  • March 1999 - Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS[45] (240 citations as of Jan 11 2023)
  • Jan 1995 - Characterization of Ionization and Matrix Suppression in Inductively Coupled ‘Cold’ Plasma Mass Spectrometry[46] (238 citations as of Jan 11 2023)
  • June 1992 - Space Charge in ICP-MS: Calculation and Implications[47] (204 citations as of Jan 11 2023)
  • July 1988 - Nonspectroscopic Interelement Interferences in Inductively Coupled Plasma Mass Spectrometry[48] (332 citations as of Jan 11 2023)

External Links[edit]

References[edit]



This article "Scott D. Tanner" is from Wikipedia. The list of its authors can be seen in its historical and/or the page Edithistory:Scott D. Tanner. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.

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  1. ↑ 1.0 1.1 "Manning Awards - Award of Distinction". Manningawards. 2001. Archived from the original on 2016-08-17.
  2. ↑ "Patents by Inventor Scott D. Tanner". Justia.com.
  3. ↑ "Scott D. Taner Inventions". Patentguru.com.
  4. ↑ 4.0 4.1 "Co-Founder of DVS Sciences". MaRSdd.com. 2011.
  5. ↑ D. J. Douglas; S.D. Tanner (1998). "Fundamental Considerations in ICP-MS". In Montaser, Akbar. Inductively Coupled Plasma Mass Spectrometry. New York: Wiley-VCH. pp. 615–679. ISBN 978-0-471-18620-5. Search this book on
  6. ↑ "US Patent 7,135,296". Google Patents. 2000-12-28. Retrieved 6 December 2022.
  7. ↑ "Fluidigm Renamed to Stanard BioTools". Globenewswirel. 2022-04-04. Retrieved 9 December 2022.
  8. ↑ "CyTOF Inventors Receive Prestigious Science and Technology Award from the Human Proteome Organization (HUPO)". GlobeNewsWire.com. September 18, 2019.
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 "Scott Tanner Biography" (PDF). StemSpecs. Nov 2005. Archived from the original (PDF) on 2009-07-04.
  10. ↑ 10.0 10.1 10.2 10.3 10.4 Ben Merison (August 6, 2009). "Interview: Raising the Bar". Highlights in Chemical Technology. 2009 (9): T65–T72. Archived from the original on 2012-10-24.
  11. ↑ "Atonic Spectrometry Viewpoint: Scott Tanner". Joural of Analytical Atomic Spectrometry. 10 (1). January 1995.
  12. ↑ "Scott D. Tanner Patents". Google Patents. Retrieved 6 December 2022.
  13. ↑ "President - DVS Sciences". 2009. Archived from the original on 2009-06-19.
  14. ↑ Holland, J. Grenville; Tanner, Scott D., eds. (4 August 2003). Plasma Source Mass Spectrometry: Applications and Emerging Technologies. Royal Society of Chemistry. ISBN 0854046038. Search this book on
  15. ↑ Holland, J. Grenville; Tanner, Scott D., eds. (2001). Plasma Source Mass Spectrometry : The New Millennium. Cambridge: Royal Society of Chemistry. ISBN 0854048952. Search this book on
  16. ↑ Holland, Grenville; Tanner, Scott D. Tanner, eds. (23 July 1999). Plasma Source Mass Spectrometry: New Developments and Applications. Cambridge, UK: Royal Society of Chemistry. ISBN 0854047492. Search this book on
  17. ↑ Holland, Grenville; Tanner, Scott D., eds. (1997). Plasma Source Mass Spectrometry : Developments and Applications. Cambridge: Royal Society of Chemistry. ISBN 0854047271. Search this book on
  18. ↑ T. Sakuma; N. Gurprasad; S.D. Tanner; A. Ngo; W.R. Davidson; H.A. McLeod; B.P-Y Lau; J.J. Ryan (1985). "The Application of Rapid Gas Chromatographic Tandem Mass Spectrometry in the Analysis of Complex Samples for Chlorinated Dioxins and Furans". In Keith, L.H.; Rappe, C.; Choudhary, G. Chlorinated Dioxins and Dibenzofurans in the Total Environment II. p. 139. OL 21212149M. Search this book on
  19. ↑ The Instantaneous Detection of Explosives by Tandem Mass Spectrometry, S.D. Tanner, W.R. Davidson and J.E. Fulford. Quantico, Virginia: US Dept of Justice. 1983. Search this book on
  20. ↑ "The Use of a Commercially Available Atmospheric Pressure Chemical Ionization Tandem Quadrupole Mass Spectrometer for the Direct Detection of Chemical Agents and Simulants, B.A. Petersen, S.D. Tanner, J.E. Fulford, B.I. Shushan and W.R. Davidson". Proc.of the 1985 Sci. Conf. On Chem. Defence Research, CRDC-SP-86007. Aberdeen Proving Ground,Maryland: USAAMCC: 15. 1986.
  21. ↑ E.R. Denoyer; D. Jacques; E. Debrah; S.D. Tanner (1995). "Determination of Trace Elements in Uranium: Practical Benefits of a New ICP-MS Lens System". Atomic Spectroscopy. 16 (1).
  22. ↑ Vladimir I. Baranov; Scott D. Tanner (1999). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). I. The RF-Field Energy Contribution in Thermodynamics of Ion-Molecule Reactions". Journal of Analytical Atomic Spectrometry. 14 (8): 1133–1142. doi:10.1039/a809889a.
  23. ↑ S.D. Tanner; V.I. Baranov (November 1999). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). II. Reduction of Interferences Produced Within the Cell". Journal of the American Society for Mass Spectrometry. 10 (11): 1083–1094. doi:10.1016/S1044-0305(99)00081-1. Unknown parameter |s2cid= ignored (help)
  24. ↑ Scott D. Tanner; Vladimir I. Baranov; Uwe Vollkopf (2000). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). III. Analytical Performance". Journal of Analytical Atomic Spectrometry. 9 (15): 1261–1269.
  25. ↑ Marcia Kaye (September 13, 2011). "Seeing Into The Soul of Cells". University of Toronto.
  26. ↑ "Lifetime Achievement Award in Plasma Spectrochemistry". Spectroscopyonline. 2020-01-13.
  27. ↑ "HUPO Awards - 2019 RECIPIENTS". HUPO. 2019.
  28. ↑ "CyTOF Inventors Receive Prestigious Science and Technology Award from the Human Proteome Organization (HUPO)". Bloomberg. Bloomberg.com. September 18, 2019.
  29. ↑ "AIMBE College of Fellows Class of 2014". AIMBE. 2014.
  30. ↑ "U of T's 2011 Inventor of the Year". UToronto. 2011.
  31. ↑ Nicolò Omenetto; Greet de Loos (20 September 2004). "Elsevier/Spectrochimica Acta Atomic Spectroscopy Award 2002". Spectrochimica Acta Part B: Atomic Spectroscopy. 59 (9): 1335. doi:10.1016/j.sab.2004.08.002. ISSN 0584-8547.
  32. ↑ Gwyn Morgan (Feb 8, 2010). "Manning Award laureates on the cutting edge". TheGlobeAndMail.com. The Globe and Mail. Archived from the original on 2014-02-14.
  33. ↑ "1999 Pittcon Editors' Awards". OOcities.org. May 1999.
  34. ↑ "Fellow of the Royal Society of Chemistry". RSC.org.
  35. ↑ "Fellow of the American Institute for Medical and Biological Engineering". AIMBE.org. 2014.
  36. ↑ Sean C. Bendall; Erin F. Simonds; Peng Qiu; El-ad D. Amir; Peter O. Krutzik; Rachel Finck; Robert V. Bruggner; Rachel Melamed; Angelica Trejo; Olga I. Ornatsky; Robert S. Balderas; Sylvia K. Plevritis; Karen Sachs; Dana Pe’er; Scott D. Tanner; Garry P. Nolan (May 2011). "Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum". Science. American Association for the Advancement of Science. 332 (6030): 6813–6822.
  37. ↑ Olga Ornatsky; Dmitry Bandura; Vladimir Baranov; Mark Nitz; Mitchell A Winnik; Scott Tanner (September 2010). "Highly Multiparametric Analysis by Mass Cytometry". Journal of Immunological Methods. Elsevier. 361 (1–2): 1–20. doi:10.1016/j.jim.2010.07.002. PMID 20655312.
  38. ↑ Dmitry R Bandura; Vladimir I Baranov; Olga I Ornatsky; Alexei Antonov; Robert Kinach; Xudong Lou; Serguei Pavlov; Sergey Vorobiev; John E Dick; Scott D Tanner (Aug 2009). "Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-Of-Flight Mass Spectrometry". Analytical Chemistry. American Chemical Society. 81 (16): 6813–6822. doi:10.1021/ac901049w. PMID 19601617.
  39. ↑ Scott D. Tanner; Vladimir I. Baranov; Dmitry R. Bandura (September 2002). "Reaction Cells and Collision Cells for ICP-MS: A Tutorial Review". Spectrochimica Acta Part B: Atomic Spectroscopy. Elsevier. 57 (9): 1361–1452. doi:10.1016/S0584-8547(02)00069-1.
  40. ↑ Vladimir I. Baranov; Zoë Quinn; Dmitry R. Bandura; Scott D. Tanner (April 2002). "A Sensitive and Quantitative Element-Tagged Immunoassay with ICPMS Detection". Analytical Chemistry. American Chemical Society. 74 (7): 1629–1636. doi:10.1021/ac0110350. PMID 12033255.
  41. ↑ Dmitry R. Bandura; Vladimir I. Baranov; Scott D. Tanner (April 2002). "Detection of Ultratrace Phosphorus and Sulfur by Quadrupole ICPMS with Dynamic Reaction Cell". Analytical Chemistry. American Chemical Society. 74 (7): 1497–1502. doi:10.1021/ac011031v. PMID 12033236.
  42. ↑ Dmitry R. Bandura; Vladimir I. Baranov; Scott D. Tanner (July 2001). "Reaction Chemistry and Collisional Processes in Multipole Devices for Resolving Isobaric Interferences in ICP–MS". Fresenius' Journal of Analytical Chemistry. Springer-Verlag. 370 (5): 454–470. doi:10.1007/s002160100869. PMID 11496972. Unknown parameter |s2cid= ignored (help)
  43. ↑ Scott D. Tanner; Vladimir I. Baranov; Uwe Vollkopf (August 2000). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part III". Journal of Analytical Atomic Spectrometry. Royal Society of Chemistry. 15 (9): 1261–1269. doi:10.1039/b002604m.
  44. ↑ Scott D. Tanner; Vladimir I. Baranov (November 1999). "A Dynamic Reaction Cell for Inductively Coupled Plasma Mass Spectrometry (ICP-DRC-MS). Part II. Reduction of Interferences Pproduced within the Cell". Journal of the American Society for Mass Spectrometry. Springer-Verlag. 10 (11): 1083–1094. doi:10.1016/S1044-0305(99)00081-1. Unknown parameter |s2cid= ignored (help)
  45. ↑ Scott D. Tanner; Vladimir I. Baranov (March 1999). "Theory, Design, and Operation of a Dynamic Reaction Cell for ICP-MS". Atomic Spectroscopy - Norwalk Connecticut. Atomic Spectroscopy. 20: 45–52.
  46. ↑ Scott D. Tanner (January 1995). "Characterization of Ionization and Matrix Suppression in Inductively Coupled 'Cold' Plasma Mass Spectrometry". Journal of Analytical Atomic Spectrometry. The Royal Society of Chemistry. 10 (11): The Royal Society of Chemistry.
  47. ↑ Scott D Tanner (June 1992). "Space Charge in ICP-MS: Calculation and Implications". Spectrochimica Acta Part B: Atomic Spectroscopy. Elsevier. 47 (6): 809–823. doi:10.1016/0584-8547(92)80076-S.
  48. ↑ George R. Gillson; Donald J. Douglas; John E. Fulford; Kenneth W Halligan; Scott D. Tanner (July 1988). "Nonspectroscopic Interelement Interferences in Inductively Coupled Plasma Mass Spectrometry". Analytical Chemistry. American Chemical Society. 60 (14): 1472–1474. doi:10.1021/ac00165a024.

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