Timirdine
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| Synonyms | EGYT‐4201 |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}} |
| Chemical and physical data | |
| Formula | C9H10ClN3S |
| Molar mass | 227.71 g·mol−1 |
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Timirdine (EGYT 4201) is an imino thiazolidine derivative that has been investigated as a potential antidepressant agent. Preclinical studies have demonstrated its activity in several behavioral models relevant to depression, suggesting that it may possess a unique pharmacological profile distinct from traditional monoaminergic antidepressants.
Pharmacology:[1] Patents (Ex 3, 12 & 18):[2][3]
It is made from a chemical called HC Yellow no. 12 [59320-13-7], which is a hair dye.
For comparison, Timirdine shares certain structural similarities to Azolimine & Clazolimine.
References
- ↑ Gyertyán, I., Petöcz, L., Gacsályi, I., Fekete, M. I. K., Tekes, K., Kápolnai, L. (January 1991). "Psychopharmacological effects of an imino‐thiazolidine derivative antidepressant candidate, EGYT‐4201". Drug Development Research. 22 (4): 385–399. doi:10.1002/ddr.430220410.
- ↑ Karoly Lempert, et al. US4665083 (1987 to Egis Pharmaceuticals PLC).
- ↑ 许孝良, 叶倩雯, & 李小年, CN106977470 (2017 to Zhejiang University of Technology ZJUT).
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