Charles Alan Lewis
| Charles Alan Lewis | |
|---|---|
| Born | Santa Rosa, California |
| 🏳️ Nationality | American |
| Other names | Charly Dansing |
| 🎓 Alma mater | Sonoma State University BA Universidad Technologica de Santiago, Doctor of Medicine University of Alabama at Birmingham M.P.H. in Epidemiology, Residency and Fellowship in Public Health and Preventive Medicine |
| 💼 Occupation | |
Charles Alan Lewis, is an American medical doctor, researcher, author and inventor. He is most widely recognized for his work in the explaining the pathophysiologic mechanisms by which the gastrointestinal immune system promotes systemic inflammation and chronic diseases of distant organs, including many diseases and disorders of the central nervous system. He is the author of the medical book "Enteroimmunology" a exposition and clinical guide to the treatment of these conditions.
Dr. Lewis and his colleagues were the first researchers to demonstrate the effect of small elevations in serum homocysteine levels, caused by marginal folic acid level, on increasing the risk for coronary artery disease,.[1][2] This work was sighted by the Institute of Medicine for their recommendations for setting higher levels of folic acid fortification of in processed foods,[3] a change that resulted in a reduced incidence of heart disease, neural tube defects and in some cancers in the United States.
After completing training in epidemiology and receiving board status in Public Health and Preventive Medicine, Dr. Lewis worked in research and medicine, mostly in Florida but also as a field epidemiologist and physician in the Dominican Republic. In collaboration with the Scheie Eye Institute and Columbia University Lewis helped identify the cause of a serve form of recessive retinitis pigmentosa, RP-14 as being caused by a mutation in the TULP1 gene,[4][5][6] Lewis worked in rural medicine for many years, where he was often the only physician in the area. In 2004, Lewis became medical director of a medical device incubator. Here he worked on the development of several devices designed to improve care of respiratory patients including the HiFLO2, a High Flow Therapy device with pressure feedback monitoring and control, and the Trach-Assist.
Prior to attending medical school, Lewis served as a volunteer in the U.S. Peace Corps in the Dominican Republic form 1980 to 1982. His area of work included teaching nutrition to elementary school teachers around the southwest region of the Dominican Republic, sanitation, health and agricultural promotion. He initiated a street project to formalize ownership boundaries in his village, and successfully lobbied for electrification of the village. He, and his fellow Peace Corps volunteers, were recipients of the Beyond War Award in 1987.
Books[edit]
- Enteroimmunology: A Guide to the Prevention and Treatment of Chronic Inflammatory Disease (2014; 3rd edition) Psy Press ISBN 978-1502706942
- College Prep Guidebook: How to Ace High School, Excel on the SAT and ACT, and Win Admission to the College of Your Choice (2014; 2nd edition) Psy Press ISBN 978-1505261578
- A Taste of Paradise: A Feast of Authentic Caribbean Cuisine and Refreshing Tropical Beverages for Health and Vitality (2012) By Susana Lewis and Dr. Charles Lewis. Psy Press ISBN 978-1938318009
- Scoundrel Hunchback Monkeys Destroy Summer (1978) Psy Press, Santa Rosa, California. By Charly Dansing
Patents[edit]
- US Patent 8,814,838 Respiratory secretion retention device, system and method
- US Patent 8,777,933 Respiratory secretion retention device, system and method
- US Patent 8,591,496 Respiratory secretion retention device, system and method
- US Patent 8,522,782 High flow therapy device utilizing a non-sealing respiratory interface and related methods
- US Patent 8,333,199 High flow therapy artificial airway interfaces and related methods
- US Patent 8,333,194 High flow therapy device utilizing a non-sealing respiratory interface and related methods
- US Patent 8,220,458 Artificial airway interfaces and methods thereof
- US Patent 7,481,219 Medicine delivery interface system
- ↑ Plasma folate adequacy as determined by homocysteine level. Lewis CA, Pancharuniti N, Sauberlich HE. Ann N Y Acad Sci. 1992 Sep 30;669:360-2.PMID 1444047
- ↑ Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease. Pancharuniti N, Lewis CA, Sauberlich HE, Perkins LL, Go RC, Alvarez JO, Macaluso M, Acton RT, Copeland RB, Cousins AL, et al. Am J Clin Nutr. 1994 Apr;59(4):940-8. PMID 8147342
- ↑ [1] Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. The National Academies Press. 1998
- ↑ Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration. Lewis CA, Batlle IR, Batlle KG, Banerjee P, Cideciyan AV, Huang J, Alemán TS, Huang Y, Ott J, Gilliam TC, Knowles JA, Jacobson SG. Invest Ophthalmol Vis Sci. 1999 Aug;40(9):2106-14. PMID 10440267
- ↑ Homozygosity and physical mapping of the autosomal recessive retinitis pigmentosa locus (RP14) on chromosome 6p21.3. Banerjee P, Lewis CA, Kleyn PW, Shugart YY, Ross BM, Penchaszadeh GK, Ott J, Jacobson SG, Gilliam TC, Knowles JA. Genomics. 1998 Mar 1;48(2):171-7. PMID 9521870
- ↑ TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Banerjee P, Kleyn PW, Knowles JA, Lewis CA, Ross BM, Parano E, Kovats SG, Lee JJ, Penchaszadeh GK, Ott J, Jacobson SG, Gilliam TC. Nat Genet. 1998 Feb;18(2):177-9. PMID 9462751
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