Claudio Nastruzzi
| Claudio Nastruzzi | |
|---|---|
 Claudio_Nastruzzi.png Claudio Nastruzzi | |
| Born | 29 March 1958 Ferrara, Italy |
| 🏳️ Nationality | Italian |
| 🏫 Education | University of Ferrara (Pharm.D., PhD) |
| 💼 Occupation | |
| Known for | Microfluidic particle engineering; controlled-release nanocarriers; lipid/polymeric delivery systems; bioencapsulation technologies |
Claudio Nastruzzi (born 29 March 1958) is an Italian pharmaceutical chemist and academic noted for contributions to nanomedicine, microfluidics, and advanced drug delivery technologies. He is Associate Professor at the Department of Chemical, Pharmaceutical and Agricultural Sciences of the University of Ferrara. His research focuses on biomaterials, encapsulation technologies, microfluidic particle generation and controlled-release formulations.
Biography
Claudio Nastruzzi was born in Ferrara, Italy. He earned a degree in Chemistry and Pharmaceutical Technology in 1983 and a PhD in Pharmaceutical Sciences in 1988 at the University of Ferrara. He later conducted postdoctoral research at ETH Zurich, focusing on pharmaceutical technologies and biomaterials.
During his postdoctoral period at ETH Zurich, Nastruzzi worked under the supervision of Professor Pier Luigi Luisi (1938–2025), a leading figure in systems chemistry and studies on the origin of life.[1]
From 1998 to 2009 he served as Associate Professor at the University of Perugia. He later returned to the University of Ferrara, where he teaches courses related to biomaterials, pharmaceutical technologies and nanomedicine.
Academic career
Nastruzzi has authored more than 180 peer-reviewed publications in nanomedicine, microfluidics, controlled-release drug delivery and biomaterials. According to his ORCID profile, he has registered more than 300 scientific works across nanomedicine, microfluidics, biomaterials and pharmaceutical technology.[2]
Independent bibliometric evaluations confirm significant impact in his field: ranking databases such as Top Italian Scientists and KIPHub report an h-index of approximately 49 and more than 8,500 citations in biomedical and pharmaceutical sciences.[3][4]
Nastruzzi also served as Guest Editor for a thematic issue of Advanced Drug Delivery Reviews (Volume 65, Issue 11), a high-impact journal in drug delivery and nanomedicine.[5]
He has participated in several European scientific networks, including COST Actions focusing on biomaterials and micro/nanofluidic technologies.[6][7][8]
Research
Nastruzzi’s research focuses on the engineering of functional pharmaceutical materials and microfabrication methodologies for nanomedicine. His work integrates colloid science, polymer chemistry and microfluidic technologies to develop advanced delivery systems for drugs, biomolecules and cells. He founded the Biomaterials & Encapsulation Laboratory (BEL), an academic group active in biomaterials, drug formulation and bioencapsulation.[9][10]
According to the University of Ferrara, his laboratory develops liposomes, microspheres, microcapsules, lipospheres, emulsions and microemulsions for pharmaceutical, biotechnological and cosmetic applications.[11][12]
Main research areas include:
- Nanoparticle and microparticle engineering
Development of lipid-based, polymeric and hybrid nanocarriers (lipospheres, liposomes, PLGA microcapsules) optimized for encapsulation efficiency, stability and controlled-release kinetics.[13][14][15]
- Bioencapsulation and hydrogel systems
Entrapment of cells, proteins and therapeutic biomolecules in polymeric and polyelectrolyte matrices for immunoisolation, regenerative medicine and biotechnology.[16][17][18]
- Microfluidic synthesis of monodisperse particles
Use of flow focusing, droplet microreactors and chip-based emulsification to precisely control particle size, morphology and composition.[19][20][21]
- Low-cost microfluidic interfacing and fabrication
Dissemination of connector designs, chip-interfacing strategies and microfabrication protocols through the Royal Society of Chemistry’s Chips & Tips platform.[22][23][24]
A further contribution by Nastruzzi to lipid-based nanocarriers is his co-authorship of a widely cited review article on microfluidic production of liposomes, published in Scientific Reports in 2016. The article discusses potential and limiting factors in microfluidic synthesis of lipid nanoparticles and is frequently referenced in drug delivery research.[25]
Selected publications
- Nastruzzi C., Cortesi R. Lipid microparticles for controlled drug delivery. Biomaterials (2000).
- Calzoni E., Cesaretti A., Polchi A., Bari M., Nastruzzi C. Microparticles for oral delivery of drugs and vaccines. Journal of Controlled Release (2019).
- Nastruzzi C., Gambari R. Encapsulation of living cells in polymeric systems. Advanced Drug Delivery Reviews (1992).
- Martucci J.F., Cortesi R., Nastruzzi C. PLGA microparticles: preparation and applications. Journal of Microencapsulation (2006).
- Calzoni E., Nastruzzi C. Microfluidic production of monodisperse polymeric nanoparticles. Lab on a Chip (2015).
- Esposito E., Cortesi R., Nastruzzi C. Microfluidic strategies for nanoparticle preparation. Microfluidics and Nanofluidics (2017).
- Casciaro B., et al., including Nastruzzi C. Liposome production by microfluidics: potential and limiting factors. Scientific Reports 6, 25876 (2016).[26]
- Nastruzzi C. (ed.). Lipospheres in Drug Targets and Delivery. CRC Press, 2000. ISBN 9780849316920.[27]
- Cortesi R., Nastruzzi C. Microfluidic droplet generation for pharmaceutical applications. Expert Opinion on Drug Delivery (2018).
External links
- Curriculum page – University of Ferrara
- ORCID profile
- Wikidata entry
- CIBIotech profile
- Top Italian Scientists
- KIPHub bibliometric profile
This article "Claudio Nastruzzi" is from Wikipedia. The list of its authors can be seen in its historical and/or the page Edithistory:Claudio Nastruzzi. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.
- ↑ "Prof. em. Pier Luigi Luisi (1938–2025)". ETH Zurich. Retrieved 2025-01-01.
- ↑ "Claudio Nastruzzi – ORCID Profile". Retrieved 2025-01-01.
- ↑ "Claudio Nastruzzi – Top Italian Scientist in Biomedical Sciences". Top Italian Scientists. Retrieved 2025-01-01.
- ↑ "Claudio Nastruzzi – Bibliometric profile". KIPHub. Retrieved 2025-01-01.
- ↑ "Advanced Drug Delivery Reviews — Volume 65, Issue 11". Elsevier. Retrieved 2025-01-01.
- ↑ "COST Action BM1302". Retrieved 2025-01-01.
- ↑ "COST Action MP0603". Retrieved 2025-01-01.
- ↑ "COST Action 865". Retrieved 2025-01-01.
- ↑ "Claudio Nastruzzi – Editorial board biography". Scholarena. Retrieved 2025-01-01.
- ↑ "Claudio Nastruzzi – Editorial profile". Walsh Medical Media. Retrieved 2025-01-01.
- ↑ "Research areas – Claudio Nastruzzi". University of Ferrara. Retrieved 2025-01-01.
- ↑ "Drug delivery, nanotechnology and microencapsulation – research team". University of Ferrara. Retrieved 2025-01-01.
- ↑ Nastruzzi, C. (2000). "Lipid microparticles for controlled drug delivery". Biomaterials.
- ↑ Martucci, J.F. (2006). "PLGA microparticles: preparation and applications". Journal of Microencapsulation.
- ↑ Cesaretti, A. (2020). "Hybrid lipid–polymer nanoparticles for sustained release". International Journal of Pharmaceutics.
- ↑ Nastruzzi, C. (1992). "Encapsulation of living cells in polymeric systems". Advanced Drug Delivery Reviews.
- ↑ Nastruzzi, C. (2003). "Alginate and polyelectrolyte microcapsules for cell immobilization". Biomacromolecules.
- ↑ "Curriculum – Claudio Nastruzzi". University of Ferrara. Retrieved 2025-01-01.
- ↑ Calzoni, E. (2015). "Microfluidic production of monodisperse polymeric nanoparticles". Lab on a Chip.
- ↑ Esposito, E. (2017). "Microfluidic strategies for nanoparticle preparation". Microfluidics and Nanofluidics.
- ↑ "Curriculum – Claudio Nastruzzi". University of Ferrara. Retrieved 2025-01-01.
- ↑ "RSC Chips & Tips – Microfluidic Interfacing". Retrieved 2025-01-01.
- ↑ "RSC Chips & Tips – Luer-lock adapters". Retrieved 2025-01-01.
- ↑ "RSC Chips & Tips – Spin coater for microfluidics". Retrieved 2025-01-01.
- ↑ "Liposome production by microfluidics: potential and limiting factors". Scientific Reports. Retrieved 2025-01-01.
- ↑ "Liposome production by microfluidics: potential and limiting factors". Scientific Reports. Retrieved 2025-01-01.
- ↑ "Lipospheres in Drug Targets and Delivery". Hoepli. Retrieved 2025-01-01.
