Jo-Anne Bright
Jo-Anne Bright (born 1976) is a forensic biologist from New Zealand. Bright is noted for contributions to the interpretation of DNA evidence, including the development of STRmix,[1] an internationally used DNA interpretation software, and improvements to DNA database searching effectiveness.[2]
Biography[edit]
Bright was born 1976 in Auckland, New Zealand to Jeffrey Raymond Bright (NZ Army Officer) and Barbara Ann Bright. She spent her first 5 years in Papakura, Auckland and then went to various different schools around New Zealand and England. Her secondary schooling at Upper Hutt College,[3] New Zealand.
She attended Victoria University of Wellington from 1995 to 1997, receiving a Bachelor of Science Degree with a double major in Biochemistry and Genetics and Molecular Biology. She then attended the University of Auckland from 1998 to 2000, receiving a Master of Science in Forensic Science. Her master's thesis, titled Forensic Analysis of Trace DNA[4] involved the development of a laboratory protocol for the forensic analysis of trace amounts of DNA recovered from casework exhibits, specifically shoes, including the optimisation of cell recovery, DNA extraction, and amplification. Bright obtained a PhD 2012–15, from the University of Auckland Research. Her thesis entitled “Informing biological models for continuous methods of DNA profile interpretation”[5] gave rise to 16 refereed publications. Her supervisors were Professor James Curran[6] and John Buckleton.
Forensic career[edit]
Bright was employed by the Institute of Environmental Science and Research (a New Zealand Crown Research Institute), the New Zealand Government forensic science service in 2002.[7] In the course of her work there, she and her colleagues create STRmix, a software program that implements probabilistic genotyping.[8][9]
STRmix. In 2010 Australia and New Zealand undertook a standardization project. As part of this project it was decided to create a software that implemented probabilistic genotyping. The software was initially called DyNamix but the name changed to STRmix after a conflict was discovered with a video game developer. the software is a joint development between Forensic Science South Australia (FSSA)[10] and ESR. The other two developers are Drs Duncan Taylor [11][better source needed] and John Buckleton. FSSA and ESR started casework in August, 2012. Currently the software is in use by New South Wales, Queensland, Western Australia, Victoria, and the Northern territory in Australia and the US Army Criminal Investigation Laboratory in the US.
DNA Database enhancements. Searching of mixtures against a database is problematic. Effective expedients include the use of wild cards. However a great many profiles are not suitable for searching against a database. By utilizing developments from the STRmix project Bright and her colleagues at the crime Sample Database unit at ESR in New Zealand, increased the number of loadable profiles to the database by 17%.
SWGDAM.[12] Bright was appointed to SWGDAM in 2014 and is involved in the Y chromosome committee. She is involved in the creation of guidelines for the interpretation of mixed and unmixed Y chromosome profiles.
References[edit]
- ↑ Taylor, D; Bright, J-A; Buckleton, J (September 2013). "The interpretation of single source and mixed DNA profiles". Forensic Science International: Genetics. 7 (5): 516–528. doi:10.1016/j.fsigen.2013.05.011.
- ↑ Bright, J-A; Taylor, D; Curran, J; Buckleton, J (March 2014). "Searching mixed DNA profiles directly against profile databases". Forensic Science International: Genetics. 9: 102–110. doi:10.1016/j.fsigen.2013.12.001.
- ↑ "Upper Hutt College". Retrieved 30 July 2015.
- ↑ "Forensic analysis of trace DNA - The University of Auckland". librarysearch.auckland.ac.nz. Retrieved 2 August 2015.
- ↑ "Informing biological models for probabilistic methods of DNA profile interpretation - The University of Auckland". librarysearch.auckland.ac.nz. Retrieved 2 August 2015.
- ↑ Curran, James. University of Auckland https://www.google.com/?gws_rd=ssl#q=James+M+Curran+stats. Retrieved 30 July 2015. Missing or empty
|title=(help) - ↑ "ESR New Zealand". ESR New Zealand. Retrieved 30 July 2015.
- ↑ "STRmix". STRmix. Retrieved 30 July 2015.
- ↑ Kelly, Hannah; Bright, Jo-Anne; Buckleton, John S.; Curran, James M. (January 2014). "A comparison of statistical models for the analysis of complex forensic DNA profiles". Science & Justice. 54 (1): 66–70. doi:10.1016/j.scijus.2013.07.003.
- ↑ "Forensic Science South Australia". Retrieved 30 July 2015.
- ↑ "Duncan lexander Taylor". Retrieved 31 July 2015.
- ↑ "Scientific Working Group on". Scientific Working Group on. Retrieved 30 July 2015.
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