Khosrow Rezvani
Khosrow Rezvani[1] is a well published,[2] NIH funded Cancer Biologist, with particular interest in colorectal cancer[3] and therapies focused on inducing cancer cell suicide.[4] As a member of the American Society for Cell Biology,[5] he has published, in a Nature group magazine, about the protein UBXN2A, which is proven to promotes colon cancer cell death by interfering with the p53-Mortalin[6] as well as "Proceedings of the National Academy of Sciences of the United States of America"[7] regarding the mechanism of cancer promotion of BRCA1 gene.[8]
He also has a keen interest hypertrophic cardiomyopathy[9] and in studying apoptosis mechanisms; in order to reduce stress-response protein expression to minimize pressure overload induced heart muscle self-destruction, cardiac wall thickening and pumping dysfunction.[10]
Multiple grants[1] were obtained by him for the University of South Dakota at Sioux City. This investment contributed to the local economy by strengthening the South Dakota's capacity for research and develop biomedical technologies.[11] In his capacity as Associate Professor, he has mentored medical students,[12] PhD candidates and young investigators[13] in furthering their knowledge of systematic research in the medical field and publishing in high impact journals.[14]
References[edit]
- ↑ 1.0 1.1 "Khosrow Rezvani Ph.D." www.usd.edu. Retrieved 9 June 2017.
- ↑ pubmeddev. "rezvani k - PubMed - NCBI". www.ncbi.nlm.nih.gov. Retrieved 9 June 2017.
- ↑ Rezvani, Khosrow (14 October 2016). "UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer". International Journal of Molecular Sciences. 17 (10). doi:10.3390/ijms17101724. PMC 5085755. PMID 27754413.
- ↑ Abdullah, Ammara; Sane, Sanam; Freeling, Jessica L.; Wang, Hongmin; Zhang, Dong; Rezvani, Khosrow (9 June 2017). "Nucleocytoplasmic Translocation of UBXN2A Is Required for Apoptosis during DNA Damage Stresses in Colon Cancer Cells". Journal of Cancer. 6 (11): 1066–1078. doi:10.7150/jca.12134. PMC 4615341. PMID 26516353.
- ↑ http://www.ascb.org/files/0601newsletter.pdf
- ↑ Sane, S.; Abdullah, A.; Boudreau, D. A.; Autenried, R. K.; Gupta, B. K.; Wang, X.; Wang, H.; Schlenker, E. H.; Zhang, D.; Telleria, C.; Huang, L.; Chauhan, S. C.; Rezvani, K. (13 March 2014). "Ubiquitin-like (UBX)-domain-containing protein, UBXN2A, promotes cell death by interfering with the p53-Mortalin interactions in colon cancer cells". Cell Death & Disease. 5 (3): e1118. doi:10.1038/cddis.2014.100. PMC 3973214. PMID 24625977. Retrieved 9 June 2017 – via www.nature.com.
- ↑ Tian, Fen; Sharma, Shilpy; Zou, Jianqiu; Lin, Shiaw-Yih; Wang, Bin; Rezvani, Khosrow; Wang, Hongmin; Parvin, Jeffrey D.; Ludwig, Thomas; Canman, Christine E.; Zhang, Dong (13 August 2013). "BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade". Proceedings of the National Academy of Sciences. 110 (33): 13558–13563. doi:10.1073/pnas.1306534110. PMC 3746927. PMID 23901102. Retrieved 9 June 2017 – via www.pnas.org.
- ↑ "BRCA1". 9 June 2017. Retrieved 9 June 2017 – via Wikipedia.
- ↑ https://professional.heart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/documents/downloadable/ucm_485610.pdf
- ↑ Auger-Messier, Mannix; Rezvani, Khosrow; Pattison, Scott (22 July 2016). "Abstract 260: Systemic Loss of p62 Reduces Pressure Overload Induced Cardiac Hypertrophy, Dysfunction and Apoptosis". Circulation Research. 119 (Suppl 1): A260–A260. Retrieved 9 June 2017 – via circres.ahajournals.org.
- ↑ "USD researcher wins research grant". siouxcityjournal.com. Retrieved 9 June 2017.
- ↑ http://www.usd.edu/-/media/files/medicine/bbs/bbs-msrp-mentor-list.ashx?la=en
- ↑ "Khosrow Rezvani". ResearchGate. Retrieved 9 June 2017.
- ↑ "Khosrow Rezvani - brin". sites.google.com. Retrieved 9 June 2017.
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