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Masaharu Seno

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Masaharu Seno
Born (1956-09-14) September 14, 1956 (age 68)
Okayama, Japan
🏳️ NationalityJapanese
🎓 Alma mater
Osaka University (PhD)
💼 Occupation
Known forCancer stem cell FGF2 Cripto-1

Masaharu Seno, Ph.D. (born 1956) is a Japanese molecular biologist and a cancer research scientist known for work on Cripto-1 gene with David S. Salomon a co-discoverd of Cripto-1.[1] [2]. He is son of a famous Japanese scientist Satimaru Seno, MD (1915-2007) [3]. His areas of research currently include cancer stem cells, microenvironment and small molecule inhibitors [4]

Life[edit]

Masaharu born in Okayama, Japan in 1956. Son of Satimaru and Fusako Seno. Studied in Osaka university, and worked after that as scientist at Takeda Chemical Industries and at 1989 he get Doctor of Philosophy from Osaka University, Japan.From 2001 he worked as Associate professor in Protein Engineering at Okayama University. He got professorship at Okayama university at 2007. He awarded Okayama Foundation Science and Technical award, 1995, and Kudodh Foundation Cancer Research, 1993.[5]

Research[edit]

Masaharu seno was in first team who succeed to sequence rat basic fibroblast growth factor and laterally succeeded to produce recombinant bFGF at takeda company [6].[7] He has been known also for his work in cancer stem cell area as he create World’s first cancer stem cell model from iPS cells.[8]

References[edit]

  1. Kannan, S.; De Santis, M.; Lohmeyer, M.; Riese Dj, 2nd; Smith, G. H.; Hynes, N.; Seno, M.; Brandt, R.; Bianco, C.; Persico, G.; Kenney, N.; Normanno, N.; Martinez-Lacaci, I.; Ciardiello, F.; Stern, D. F.; Gullick, W. J.; Salomon, D. S. (February 7, 1997). "Kannan S, et al. . J Biol Chem. 1997 Feb 7;272(6):3330-5.)". Journal of Biological Chemistry. 272 (6): 3330–3335. doi:10.1074/jbc.272.6.3330. PMID 9013573. Unknown parameter |s2cid= ignored (help)
  2. Bianco, C.; Kannan, S.; De Santis, M.; Seno, M.; Tang, C. K.; Martinez-Lacaci, I.; Kim, N.; Wallace-Jones, B.; Lippman, M. E.; Ebert, A. D.; Wechselberger, C.; Salomon, D. S. (March 26, 1999). "Bianco C, et al. 1999 Mar 26;274(13):8624-9.)". Journal of Biological Chemistry. 274 (13): 8624–8629. doi:10.1074/jbc.274.13.8624. PMID 10085099. Unknown parameter |s2cid= ignored (help)
  3. Okada, Shigeru (October 2007). "Okada, S. A Tribute to Professor Satimaru Seno. Int J Hematol 86, 205–206 (2007)". International Journal of Hematology. 86 (3): 205–206. doi:10.1532/IJH97.07999. PMID 29349746. Unknown parameter |s2cid= ignored (help)
  4. "Research". Overviow for research on google scholar. Retrieved June 17, 2021.
  5. "Masaharu,Seno". researchmap. Retrieved June 17, 2021.
  6. "Tsutomu Kurokawa, Masaharu Seno, Koichi Igarashi, Nucleotide sequence of rat basic fibroblast growth factor cDNA, Nucleic Acids Research, Volume 16, Issue 11, 10 June 1988, Page 5201".
  7. Iwane, Makoto; Kurokawa, Tsutomu; Sasada, Reiko; Seno, Masaharu; Nakagawa, Shizue; Igarashi, Koichi (July 31, 1987). "Iwane M, Kurokawa T, Sasada R, Seno M, Nakagawa S, Igarashi K. Expression of cDNA encoding human basic fibroblast growth factor in E. coli. Biochem Biophys Res Commun. 1987 Jul 31;146(2)". Biochemical and Biophysical Research Communications. 146 (2): 470–477. doi:10.1016/0006-291X(87)90553-5. PMID 3304281.
  8. "World's first cancer stem cell model from iPS cells". Okayama University. Retrieved June 17, 2021.

External links[edit]

  • [1], Google Scholar
  • [2], Google Patents
  • [3], Google Patents
  • [4], Okayama University


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