Sriram Kosuri
| Sriram Kosuri | |
|---|---|
.jpg) Kosuri in Camden, Maine | |
| Born | North Carolina |
| 🏫 Education | University of California, Berkeley (Bachelor of Science) Massachusetts Institute of Technology (ScD) |
| 💼 Occupation | |
| 👩 Spouse(s) | Karin Alm |
| 👶 Children | 2 |
| 🏅 Awards | NIH New Innovator Award (2014) Searle Scholar Award (2015) |
Sriram “Sri” Kosuri is an American scientist, entrepreneur, and academic known for work in synthetic biology, functional genomics, and bioinformatics. He is a co-founder and CEO of Octant and an associate professor in the Department of Chemistry and Biochemistry at the University of California, Los Angeles (UCLA).[1][2]
Early life and education
Kosuri was born in North Carolina in 1979 (age 46) and raised in New Jersey, with time in Philadelphia and Kansas. He earned a Bachelor of Science in Bioengineering from the University of California, Berkeley and a ScD (Doctor of Science) in Biological Engineering from the Massachusetts Institute of Technology (MIT).[1]
Career
Kosuri’s career spans academic research and commercial biotechnology. Early in his career, he worked at the Wyss Institute and at Harvard University, where he contributed to technologies in gene synthesis, DNA information storage, gene editing, and large-scale multiplexed assays.[1]
He was involved with the founding teams or advisory boards of multiple companies in the synthetic biology and biotech sectors, including serving as a co-founder and CEO of Octant. Kosuri has been described as having helped build technologies, labs, and companies over two decades focused on creating large-scale experimental approaches to protein biochemistry, human genetic variation, gene regulation, chemical biology, synthetic biology, and functional genomics.[1]
Teaching and mentorship
Kosuri is an associate professor (previously assistant professor) in the UCLA Department of Chemistry and Biochemistry, where his laboratory conducts empirical, high-throughput investigations into protein function and genetic variation.[3]
Kosuri teaches and mentors students at UCLA in chemistry/biochemistry and related research areas.[4][5]
Research
Kosuri's research interests include scalable experimental methods for studying proteins and genetic variation, synthetic biology tools, and applications of high-throughput assays. His publications include work on scalable gene synthesis and related molecular-biology technologies.[1][6]
Awards and honors
Kosuri has received several major early-career awards, including the NIH New Innovator Award (2014) and the Searle Scholar Award (2015). He was one of 15 Searle Scholars selected in 2015 and was the only UCLA scientist to receive the award that year.[1][7]
Selected publications
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- Next-generation digital information storage in DNA
- Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
- Large-scale de novo DNA synthesis: technologies and applications
- Causes and effects of N-terminal codon bias in bacterial genes
- Composability of regulatory sequences controlling transcription and translation in Escherichia coli
- Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
External links
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 "Octant". www.octant.bio. Retrieved 2025-11-08.
- ↑ "Sriram Kosuri". Science Friday. Retrieved 2025-11-08.
- ↑ "Sriram Kosuri". Science Friday. Retrieved 2025-11-08.
- ↑ "Sriram Kosuri at University of California Los Angeles (UCLA) | Rate My Professors". www.ratemyprofessors.com. Retrieved 2025-11-08.
- ↑ Sriram Kosuri Profile, ResearchGate, https://www.researchgate.net/profile/Sriram-Kosuri, retrieved 8 November 2025
- ↑ Kosuri, Sriram; Eroshenko, Nikolai; Leproust, Emily M.; Super, Michael; Way, Jeffrey; Li, Jin Billy; Church, George M. (December 2010). "Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips". Nature Biotechnology. 28 (12): 1295–1299. doi:10.1038/nbt.1716. ISSN 1546-1696. PMC 3139991. PMID 21113165.
- ↑ "Sriram Kosuri named 2015 Searle Scholar". stemcell.ucla.edu. Retrieved 2025-11-08.
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