Theodore Mathuram
Theodore Lemuel Mathuram was born on June 2nd 1986 at Tiruchirappalli, Tamil Nadu, India to Dr Joseph Mathuram and Mrs Muriel Mathuram. He is the great-grandson of E.P. Mathuram (who won the Tiruchirapalli Lok Sabha Constituency as First Member of the Parliament in 1952).
Education
Theodore attended his early schooling at Campion Anglo Indian Higher Secondary School.
Theodore pursued his Bachelor’s in Zoology at the Bishop Heber College (Bharathidasan University) and later went on to attend Royal Melbourne Institute of Technology, where he earned a Master’s in Biotechnology. He later returned to India to pursue a Post Graduate Diploma in Stem Cell Technology and Tissue Engineering at the University of Madras (Madras, India). He later started working on his Ph.D in Biotechnology exploring avenues in Cancer. He was the first to repurpose the "orphan drug" Tideglusib for Neuroblastoma and Ovarian cancers using in vitro studies.[1][2] His recent publication on GSK-3 explores the significance of GSK-3 as an 'Ace' among kinases.[3]
Positions
He pursued various postdoctoral positions at Nova Southeastern University, Baylor College of Medicine, University at Buffalo and University of Oklahoma.
He currently holds a Biology Faculty position at the Oklahoma School of Science and Mathematics with additional responsibilities as Director of the Mentorship Program and the IRSP (Investigative Research Scholar Program).
References
- ↑ Mathuram, Theodore Lemuel; Ravikumar, Vilwanathan; Reece, Lisa M.; Karthik, Selvaraju; Sasikumar, Changam Sheela; Cherian, Kotturathu Mammen (2016-09). "Tideglusib induces apoptosis in human neuroblastoma IMR32 cells, provoking sub-G 0 /G 1 accumulation and ROS generation". Environmental Toxicology and Pharmacology. 46: 194–205. doi:10.1016/j.etap.2016.07.013. Check date values in:
|date=(help) - ↑ Mathuram, Theodore Lemuel; Ravikumar, Vilwanathan; Reece, Lisa M.; Sasikumar, Changam Sheela; Cherian, Kotturathu Mammen (2017). "Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells". Journal of Environmental Pathology, Toxicology and Oncology. 36 (4): 321–344. doi:10.1615/JEnvironPatholToxicolOncol.2017025018. ISSN 0731-8898.
- ↑ Mathuram, Theodore Lemuel (2024-05-15). "GSK-3: An "Ace" Among Kinases". Cancer Biotherapy and Radiopharmaceuticals. doi:10.1089/cbr.2024.0025. ISSN 1084-9785.
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