Ursula Reinstein

Ursula I. Reinstein (née Heczko) (born May 1964) is an Austrian veterinarian and a microbiological researcher.

Early life and education

Born in Lohr am Main, Germany, Reinstein grew up in Munich. She attended the University of Veterinary Medicine Vienna and completed her doctoral thesis in cancer research, culminating in a peer-reviewed publication in the British Veterinary Journal on the sequence of an exon of the feline p53 gene-mutation in a lymphosarcoma.

Career

Reinstein practiced in an animal veterinary office in Vienna, and then moved on to microbiology research and food-borne diseases. During the 1990s, she was appointed as the food control officer for the city of Vienna.

In 1998, she began a post-doctoral position in the biotechnology laboratory of Brett Finlay OC OBC FRSC, an expert on the molecular understanding of the ways bacteria infect their hosts, at the University of British Columbia (UBC), Vancouver. During her three-year tenure, Reinstein published six peer-reviewed scientific papers.

File:SegmentedFillamentousBacteria.png

Scanning electron micrographs depicting segmented filamentous bacteria and a lack of colonization of EPEC

While at UBC, Reinstein (under her maiden name Heczko), discovered a probiotic means of preventing infection by E. coli. After failing repeatedly to achieve a standard model of infection by inoculation of enteropathogenic Escherichia coli into a set of experimental rabbits, she performed electron microscope studies to try to understand why these animals were seemingly immune to the pathogen. This led to her discovery of and later publishing that segmented filamentous bacteria prevent colonization of enteropathogenic Escherichia coli O103 in rabbits, making the cover of The Journal of Infectious Diseases.

Reinstein has also been published by the American Journal of Physiology and contributed to the peer-reviewed Emerging Infectious Diseases published by the Centers for Disease Control and Prevention.

In 2001, Reinstein and three colleagues completed a study about enteropathogenic Escherichia coli infection. Supported by a Howard Hughes International Research Scholar Award and a grant from the Medical Research Council of Canada, the findings were published by the American Society for Microbiology.

Personal life

Reinstein and ophthalmologist Dan Reinstein met and married in Vancouver, Canada. In 2001, they moved to the UK, where they live in central London with their three children, Julia, Maxwell and Oscar. She continues to work in research-related activity at the London Vision Clinic, where she has been a director since 2007.

Publications

• Heczko, Ursula; Carthy, Chris M; O'Brien, Bronwyn A; Finlay, B Brett (2001). "Decreased Apoptosis in the Ileum and Ileal Peyer's Patches: a Feature after Infection with Rabbit Enteropathogenic Escherichia coli O103". Infection and Immunity. 69 (7): 4580–4589.
• Heczko, Ursula; Smith, Valerie C; Meloche, R Mark; Buchan, Alison MJ; Finlay, B Brett (2000). "Characteristics of Helicobacter pylori attachment to human primary antral epithelial cells". Microbes and Infection. 2 (14): 1669–1676.
• Heczko, U; Abe, A; Finlay, BB (March 2000). "Segmented filamentous bacteria prevent colonization of enteropathogenic Escherichia coli O103 in rabbits". The Journal of Infectious Diseases. 181 (3): 1027–33.
• Heczko, Ursula; Abe, Akio; Finlay, B Brett (2000). "In vivo interactions of rabbit enteropathogenic Escherichia coli O103 with its host: an electron microscopic and histopathologic study". Microbes and Infection. 2 (1): 5–16. PMID 10717535.
• Raupach, B; Mecsas, J; Heczko, U; Falkow, S; Finlay, BB (1999). "Bacterial epithelial cell cross talk": 137–161.
• Abe, Akio; Heczko, Ursula; Hegele, Richard G; Finlay, B Brett (1998). "Two enteropathogenic Escherichia coli type III secreted proteins, EspA and EspB, are virulence factors". Journal of Experimental Medicine. 188 (10): 1907–1916.
• Richter-Dahlfors, Agneta; Heczko, Ursula; Meloche, R Mark; Finlay, B Brett; Buchan, Alison MJ (1998). "Helicobacter pylori-infected human antral primary cell cultures: effect on gastrin cell function". American Journal of Physiology. Gastrointestinal and Liver Physiology. 275 (3): G393–G401.
• Mayr, B; Heczko, U; Schellander, K; Schleger, W; Reifinger, M (Jul 1993). "Sequence of an exon of the feline p53 gene--mutation in a lymphosarcom". The British Veterinary Journal. 149 (4): 387–90.

External links

• Ursula Heczko's research works, University of British Columbia-Vancouver

This article "Ursula Reinstein" is from Wikipedia. The list of its authors can be seen in its historical and/or the page Edithistory:Ursula Reinstein. Articles copied from Draft Namespace on Wikipedia could be seen on the Draft Namespace of Wikipedia and not main one.

📰 Article(s) of the same category(ies)

• Dinah Ashley-Cooper, Countess of Shaftesbury
• Greg Dickens
• Adam Fulton
• Mandisa Greene

---