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Cradle Bio

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Cradle Bio
Private
ISIN🆔
IndustryBiotechnology · Artificial intelligence
Founded 📆May 2021; 5 years ago (2021-05)
Founders 👔Stef van Grieken · Jelle Prins · Elise de Reus · Eli Bixby · Harmen van Rossum
Headquarters 🏙️,
Amsterdam
,
Number of locations
Amsterdam (HQ); Zurich, Switzerland
Area served 🗺️
Key people
Stef van Grieken (CEO)
Products 📟 Software for protein engineering
Members
Number of employees
🌐 Websitewww.cradle.bio
📇 Address
📞 telephone

Cradle Bio B.V. (doing business as Cradle) is a Dutch–Swiss biotechnology company that develops software using machine learning for protein engineering. It was founded in 2021 and is based in Amsterdam, with an office in Zürich.[1][2]

History

Cradle was founded in 2021 by Stef van Grieken, Jelle Prins, Elise de Reus, Eli Bixby and Harmen van Rossum.[1] In November 2022 the company raised a €5.5 million seed round led by Index Ventures.[2] It raised a US$24 million Series A financing in November 2023, led by Index Ventures.[3] In 2024 the company announced a US$73 million Series B round led by IVP.[4][5]

Technology

According to TechCrunch, Cradle's platform applies techniques derived from large language models to generate amino‑acid sequence variants predicted to exhibit user‑selected properties (such as stability or binding).[1] Subsequent coverage reported use by pharmaceutical companies and performance improvements in protein design experiments.[6]

Recognition

Cradle was listed by Wired as one of the "Hottest Startups in Amsterdam in 2024" and was included in Bloomberg's "25 European Startups to Watch" list in 2025.[7][8]

See also

References

  1. ↑ 1.0 1.1 1.2 "Protein programmers get a helping hand from Cradle's generative AI". TechCrunch. 16 November 2022.
  2. ↑ 2.0 2.1 "Cradle raises €5.5m to 'reverse engineer' biology with machine learning". Sifted. 16 November 2022.
  3. ↑ "GenAI biotech Cradle raises $24m Series A led by Index Ventures". Sifted. 14 November 2023.
  4. ↑ "Cradle builds out its protein-design AI platform (and wet lab) with $73M in new funding". TechCrunch. 26 November 2024.
  5. ↑ "Cradle Bio raises $73M Series B to sell pharma its protein-making AI software". Endpoints News. 26 November 2024.
  6. ↑ "Cradle's AI-powered protein programming platform levels up with $24M in new funding". TechCrunch. 27 November 2023.
  7. ↑ "The Hottest Startups in Amsterdam in 2024". Wired. 14 October 2024. Archived from the original on 14 October 2024.
  8. ↑ "25 European Startups to Watch". Bloomberg. 9 June 2025. Retrieved 25 July 2025.



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