Gian Luca Grazi
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Italian HepatoPancreatoBiliary surgeon, known for his clinical and scientific activities in the field of surgery of the liver, of the pancreas and of the biliary tree.
| Gian Luca Grazi, MD, PhD | |
|---|---|
| Born | August 12th, 1961 |
| Medical career | |
| Profession | Surgeon |
| Institutions | University of BolognaUniversity of Nebraska Medical CenterNational Cancer Center "Regina Elena" IRCCS |
| Sub-specialities | Hepatobiliary and Pancreatic Surgery |
Education and career[edit]
Gian Luca Grazi was admitted to the Medical Faculty of the University of Bologna in 1980 and completed his studies with the final evaluation of "summa cum laude".[1]
He completed a degree thesis discussing the surgical treatment of liver haemangiomas.
In May 1987 he was admitted to attend the 95th Course of the Italian Medical Army Corps at the Military School in Florence. As lieutenant he was assigned to the 21st "Romagna" Campaign Artillery Group in Bologna, in service until 4 August 1988.
From November 1988 to August 1989 he was Visiting Faculty at the Transplant Unit of the University of Nebraska Medical Center, in Omaha, Nebraska, U.S.A., under the supervision of surgeon Dr. Byers W. Shaw, MD
In 1989 he was admitted to the 3rd cycle of the PhD in "Biological Markers of Tumors of the Gastrointestinal Tract". He obtained the PhD title on June 8, 1992 with a thesis on "Clinical evaluation of tumor markers in hepatic neoplasms, with particular study of the application of de-gamma-carboxyprothrombin".[2]
In August 1992 he was hired by the University of Bologna, initially as a graduate technician and then as a researcher. With this role he began working as a surgeon within the Policlinico Sant'Orsola-Malpighi, initially in the Surgery Clinic II, directed by Prof. Giuseppe Gozzetti, and subsequently with Prof. Alighieri Mazziotti and then with Prof. Antonio Daniele Pinna.
From November 1999 to May 2010 he held the role of head of the transplant phase within the "Liver Transplant Review" program.
Since December 2004 he has held the position of Associate Professor of General Surgery at the University of Bologna, carrying out his clinical activity at the Policlinico Sant'Orsola-Malpighi, in Bologna.
On 1 February 2022 he took up the position of Full Professor of General Surgery at the University of Ferrara.
On 25 November 2022 he was the winner of the comparative procedure for the position of Full Professor of General Surgery at the University of Florence.
Surgical activities[edit]
The surgical activity of Gian Luca Grazi has developed mainly in the field of surgery of the liver, of the pancreas and the biliary tract. In his career as a surgeon, he has personally performed more than 1200 liver resections, more than 160 Whipple procedures and 288 liver transplants. On 9 April 1986 he took part in the first liver transplant performed at the University of Bologna.[3]
The most appreciated scientific work was published in July 2001. It was the demonstration that the results of liver resections had improved since their introduction in the clinical field and these improvements gave the procedure a superior added value.[4]
In Bologna, in August 2008, he took part in one of the rare multi-organ transplants performed in the world, participating in the simultaneous heart, liver and kidney transplant.[5]
In the months of May-June 2010 he participated in the television series 'Transplants. Fates Crossed'', which was a docu-fiction broadcast by Fox Life[6]
On 1 June 2010 he was appointed chief of the HepatoBilioPancreatic Surgery Unit of the National Cancer Institute "Regina Elena" IRCCS, in Rome[7]
In March 2021 he performed one of the first minimally invasive right hepatectomies using the “Da Vinci” surgical robot in Italy and the first in the Lazio Region, removing a large liver adenoma in a 22-year-old young woman.[8]
The most recent interest concerns the execution of robotic resective liver surgery[9]
Research and Scientific activities[edit]
From June 2010 until 2016 he was "member-at-large" of the board of the international scientific society "European-African Hepato-Pancreato-Biliary Association" (E-AHPBA)[10]. The primary mission of the Association is to be the leading interdisciplinary organization for HPB surgical science and education in the region and to provide an international forum to showcase developments and cutting-edge science in HPB surgery
Founding member of scientific societies:
- "International Liver Cancer Association" (ILCA), scientific society dedicated to the study of hepatocellular carcinoma.
- “PeriOperative Italian Society” (P.O.I.S.): the purpose of the society is to promote and disseminate the concept of the perioperative path of the surgical patient, with particular attention to the definition of recommendations and diagnostic and therapeutic guidelines that can guarantee the best result, in compliance with the correct therapeutic procedures.[11]
- “Italian Association of Hepatobiliary and Pancreatic Surgery (AICEP). AICEP is a scientific and cultural association whose main purpose is to promote the clinical, technical and scientific progress of Italian Surgery in the Hepato-Bilio-Pancreatic field.[12]
National Coordinator of the Scientific Research Program of Relevant Interest (PRIN) Year 2008 - prot. 2008WRBYPE entitled "Biological age of the pre-transplant liver and age difference between donor and recipient as new predictors of the function of the transplanted organ".[13][14]
Member of the working group for the extension of the "Hepatocarcinoma" Guidelines 2019[15] and 2020[16] Editions of the Italian Association of Medical Oncology (A.I.O.M.)
As of May 2022, Gian Luca Grazi is the author of 780 scientific publications, including 21 book chapters and 366 original papers. Of these 366 papers, 334 appeared in indexed journals and 301 have also an impact factor.[17]
According to the 2021 InCites Journal Impact Factors, released by Clarivate on June 28, 2022, the global publication score is 2,986.375 (average per publication 9,922).
According to the evaluation obtainable with Scopus in January 2023, the h-index value is 80.[18]
As of May 2022, Gian Luca Grazi has given lectures and scientific reports at 31 international meetings and 128 national congresses.[1]
Furthermore, Gian Luca Grazi regularly carries out peer review activities for the main surgical scientific journals.[19]
Web activities[edit]
Gian Luca Grazi is the creator and manager of the Internet site "Chirurgia del Fegato"[20]. The site was opened in February 2002[21] and at the time was among the first ever to provide information on this type of disease.and to systematically provide news and advice to patients and their relatives on the main diseases of the liver, pancreas and biliary tract. This website has more than 1000 unique visitors daily.[22]
The site's early activity was thoroughly analyzed and published in the scientific journal Archives of Surgery (today Jama Surgery)[23]
In addition to the section dedicated more specifically to clinical activity which is aimed at patients and their doctors, the website also offers a section for hepatobiliopancreatic surgeons, with an extensive review of the history of liver surgery[24] and a vast library of scientific works cover the main aspects of surgery of the liver, pancreas and biliary tract.[25]
References[edit]
- ↑ 1.0 1.1 Curriculum Vitae Prof. Gian Luca Grazi at IFO.it
- ↑ Grazi, Gian Luca; Mazziotti, Alighieri; Legnani, Cristina; Jovine, Elio; Miniero, Rita; Gallucci, Antonio; Palareti, Gualtiero; Gozzetti, Giuseppe (July 1995). "The role of tumor markers in the diagnosis of hepatocellular carcinoma, with special reference to the des-gamma-carboxy prothrombin". Liver Transplantation and Surgery. 1 (4): 249–255. doi:10.1002/lt.500010410.
- ↑ Gozzetti, G.; Cavallari, A.; Bellusci, R.; Mazziotti, A.; Jovine, E.; Grazi, G. L.; Shehadeh, R. (1989-01-31). "[Liver transplant in Bologna. Results of the first 8 cases]". Minerva Chirurgica. 44 (1–2): 9–14. ISSN 0026-4733. PMID 2651996.
- ↑ Grazi, Gian Luca; Ercolani, Giorgio; Pierangeli, Filippo; Del Gaudio, Massimo; Cescon, Matteo; Cavallari, Antonino; Mazziotti, Alighieri (July 2001). "Improved Results of Liver Resection for Hepatocellular Carcinoma on Cirrhosis Give the Procedure Added Value". Annals of Surgery. 234 (1): 71. doi:10.1097/00000658-200107000-00011. ISSN 0003-4932. PMC 1421950. PMID 11420485.
- ↑ Carlino, il Resto del (2008-08-20). "Trapianto di cuore, fegato e rene La paziente è sveglia, il primo pasto". il Resto del Carlino (in italiano). Retrieved 2023-01-17.
- ↑ Digital-News.it (2010-05-10). "Trapianti. Destini incrociati, da stasera la nuova docu-fiction di Fox Life | Digital-News.it". www.digital-news.it (in italiano). Retrieved 2023-01-17.
- ↑ "REGINA ELENA: GRAZI DIRETTORE CHIRURGIA EPATOBILIOPANCREATICA". Salute H24. Retrieved 2023-01-17.
- ↑ Regina elena: epatectomia destra con il robot in giovane di 22 anni, retrieved 2023-01-17
- ↑ Coletta, Diego; Ossola, Paolo; Parrino, Chiara; Oddi, Andrea; D'Annibale, Marco; Perri, Pasquale; De Peppo, Valerio; Grazi, Gian Luca (2020-11-01). "Robotic Liver Resections: Application of Difficulty Score Systems to an Initial Experience. Is a Specific Robotic Difficulty Score Necessary?". Journal of Laparoendoscopic & Advanced Surgical Techniques. 30 (11): 1177–1182. doi:10.1089/lap.2020.0119. ISSN 1092-6429.
- ↑ "E-AHPBA – European-African Hepato-Pancreato-Biliary Association". Retrieved 2023-01-17.
- ↑ "Statuto – ERAS POIS" (in italiano). Retrieved 2023-01-17.
- ↑ "Chi siamo". AICEP (in italiano). Retrieved 2023-01-17.
- ↑ Capri, Miriam; Olivieri, Fabiola; Lanzarini, Catia; Remondini, Daniel; Borelli, Vincenzo; Lazzarini, Raffaella; Graciotti, Laura; Albertini, Maria Cristina; Bellavista, Elena; Santoro, Aurelia; Biondi, Fiammetta; Tagliafico, Enrico; Tenedini, Elena; Morsiani, Cristina; Pizza, Grazia (April 2017). "Identification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants". Aging Cell. 16 (2): 262–272. doi:10.1111/acel.12549. PMC 5334540. PMID 27995756.
- ↑ academic.oup.com. doi:10.1093/gerona/gly048 https://academic.oup.com/crawlprevention/governor?content=%2fbiomedgerontology%2fadvance-article%2fdoi%2f10.1093%2fgerona%2fgly048%2f4937953. Retrieved 2023-01-17. Missing or empty
|title=(help) - ↑ Linee guida EPATOCARCINOMA Edizione 2019 - Aggiornata a ottobre 2019
- ↑ Linee guida EPATOCARCINOMA Edizione 2020
- ↑ "Gian Luca Grazi". scholar.google.it. Retrieved 2023-01-17.
- ↑ "Scopus preview - Grazi, Gian Luca - Author details - Scopus". www.scopus.com. Retrieved 2023-01-17.
- ↑ "Web of Science". www.webofscience.com. Retrieved 2023-01-17.
- ↑ "Chirurgia del fegato e del pancreas". Chirurgia del Fegato (in italiano). Retrieved 2023-01-17.
- ↑ "chirurgiadelfegato.it whois lookup - who.is". who.is. Retrieved 2023-01-17.
- ↑ "ShinyStat™". s1.shinystat.com. Retrieved 2023-01-17.
- ↑ jamanetwork.com. doi:10.1001/archsurg.141.12.1176 https://jamanetwork.com/journals/jamasurgery/fullarticle/399463. Retrieved 2023-01-17. Missing or empty
|title=(help) - ↑ "Storia della Chirurgia del Fegato". Chirurgia del Fegato (in italiano). Retrieved 2023-01-17.
- ↑ "The HPB Library". Chirurgia del Fegato (in italiano). Retrieved 2023-01-17.
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