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Sami J Barmada

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Professor
Sami J Barmada
Born1976
🏳️ NationalityAmerican
💼 Occupation
👪 RelativesBicher barmada (father)
Mustafa Bey Barmada (great grandfather)
🏅 AwardsAmerican Society for Clinical Investigation (2014)
🌐 Websitehttps://www.barmadalab.com/
🥚 TwitterTwitter=
label65 = 👍 Facebook

Sami Jihad Barmada (Arabic: سامي جهاد برمدا) ; (born 1976), is an American neuroscientist , professor, and academic administrator of Syrian descent.[1] Barmada serves on the executive advisory board of the Robert Packard Center for ALS Research[2], and acts as a director of Michigan Brain Bank.[3]

Early life[edit]

Sami Barmada was born in Pittsburgh, PA, USA in 1976 to a Syrian family . He is the son of Bicher Barmada, Thoracic Surgeon and Mamdouha Ahdab-Barmada, Pathologist, and his great grandfather was Mustafa Bey Barmada (the former Governor-General of the State of Aleppo).

Education[edit]

Sami Barmada obtained his BS from University of Pittsburgh. He received his PhD in the Medical Scientist Training Program at Washington University. And he did his neurology residency, at the University of California, San Francisco (UCSF) school of medicine.[3]

Awards and honors[edit]

Barmada was awarded the Young Physician Scientist Award from the American Society for Clinical Investigation in 2014. He is also the recipient of the inaugural Angela Dobson and Lyndon Welch Research Professorship at the University of Michigan. While at the University of Pittsburgh, PA, he received a University Scholarship and the College of Arts and Sciences Alumni Merit Award. At Washington University in St. Louis, he earned the Richard and Mildred Poletsky Award from the Alzheimer's Disease Research Center, the Irwin Levy Award for Excellence in Neurology and Neurological Surgery, and was named a Spencer & Ann Olin Medical Scientist Fellow.[3]

According to Google Scholar, Barmada has an h-index of 34 [4] according to the Scopus one of 25.[5] He is a fellow member of the American Neurological Association since 2003, and a fellow member of American Association of Neurology since 1997 and a fellow member of Society for Neuroscience since 2002.

Selected journal publications[edit]

  • Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis[6]
  • Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models[7]
  • Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability[8]
  • Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury[9]
  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1[10]
  • RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response[11]
  • Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD[12]
  • Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology[13]

References[edit]

  1. "People". barmada lab. Retrieved 2021-08-24.
  2. "Sami Barmada, MD, PhD | The Robert Packard Center for ALS Research at Johns Hopkins". www.packardcenter.org. Retrieved 2022-08-10.
  3. 3.0 3.1 3.2 "Sami Barmada, MD, PhD | Neurology | Michigan Medicine". Neurology. 2014-04-01. Retrieved 2021-08-25.
  4. "Sami Barmada". scholar.google.com. Retrieved 2021-10-05.
  5. "Scopus preview - Barmada, Sami J. - Author details - Scopus". www.scopus.com. Retrieved 2021-10-05.
  6. "Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis". scholar.google.com. Retrieved 2022-08-10.
  7. "Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models". scholar.google.com. Retrieved 2022-08-10.
  8. "Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability". scholar.google.com. Retrieved 2022-08-10.
  9. "Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury". scholar.google.com. Retrieved 2022-08-10.
  10. "Guidelines for the use and interpretation of assays for monitoring autophagy". scholar.google.com. Retrieved 2022-08-10.
  11. "RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response". scholar.google.com. Retrieved 2022-08-10.
  12. Krishnan, Gopinath; Raitcheva, Denitza; Bartlett, Daniel; Prudencio, Mercedes; McKenna-Yasek, Diane M.; Douthwright, Catherine; Oskarsson, Björn E.; Ladha, Shafeeq; King, Oliver D.; Barmada, Sami J.; Miller, Timothy M. (2022-05-19). "Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD". Nature Communications. 13 (1): 2799. doi:10.1038/s41467-022-30387-4. ISSN 2041-1723. PMC 9119980 Check |pmc= value (help). PMID 35589711 Check |pmid= value (help).
  13. François-Moutal, Liberty; Scott, David Donald; Ambrose, Andrew J.; Zerio, Christopher J.; Rodriguez-Sanchez, Marina; Dissanayake, Kumara; May, Danielle G.; Carlson, Jacob M.; Barbieri, Edward; Moutal, Aubin; Roux, Kyle J. (2022-05-17). "Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology". Scientific Reports. 12 (1): 8140. doi:10.1038/s41598-022-12191-8. ISSN 2045-2322. PMC 9114370 Check |pmc= value (help). PMID 35581326 Check |pmid= value (help).

External links[edit]



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