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Juan Ramón Cabrera Garrido

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Juan Ramón Cabrera Garrido
Born (1944-08-31) August 31, 1944 (age 79)
Granada, Spain
🏳️ NationalitySpanish
💼 Occupation
Medical Doctor. Vascular Surgeon
📆 Years active  1970-present

Juan Ramón Cabrera Garrido (Granada, August 31, 1944) is a Spanish physician, vascular surgeon, researcher and the inventor of Microfoam sclerosing agents.

Biography outline[edit]

Born in 1944 in Granada (Spain), he graduated in Medicine (1970) at its University, where he was awarded his Doctorate (Summa cum laude) in 1977 and was a professor at the School of Medicine.[1] Founding member (1984) of the Andalusian Society of Angiology and Vascular Surgery,[2] he worked in the Regional Department of Vascular Surgery of the Virgen de las Nieves University Hospital of Granada as Head of Section until he took voluntary unpaid leave in 1996. Since then, he has dedicated his time to his private practice and research.[3]

His investigations led to the discovery in 1993 of Microfoam sclerosing agents,[4] a new injectable pharmaceutical form for the non-surgical treatment of all types of varicose veins,[5] venous malformations,[6][7] varicose ulcers,[6] varicoceles and hemorrhoids.

Based on his patent[8] of this novel product, the British multinational BTG developed a pharmaceutical specialty (the first of Spanish origin approved by the FDA) designated Varithena.[9] This has been used in the United States since 2014 as an alternative to surgery and other ablative techniques for the treatment of large varicose veins.[10]

Research and development[edit]

In relation to the aforementioned discovery, he published articles on its application and outcomes in international scientific journals:

  • Treatment of Varicose Long Saphenous Veins with Sclerosant in Microfoam Form: Long-Term Outcomes.[11]
J Cabrera, MA García-Olmedo • Aug 2000 • Phlebology.
  • Sclerosants in microfoam. A new approach in angiology.[12]
J Cabrera, MA García-Olmedo • Jan 2002 • International angiology: a journal of the International Union of Angiology.
  • Treatment of venous malformations with sclerosant in microfoam form​.[13]
J Cabrera, J Cabrera Jr, MA García-Olmedo, P Redondo • Nov 2003 • Arch Dermatol.
  • Sclerosing treatment of vascular malformations.[14]
J Cabrera, P Redondo • Feb 2004 • Anales del sistema sanitario de Navarra.
  • Ultrasound-guided injection of polidocanol microfoam in the management of venous leg ulcers.[15]
J Cabrera, P Redondo, A Becerra et al • Jun 2006 • Archives of Dermatology.
  • Foam Treatment of Venous Leg Ulcers. The Initial Experience.[16]
J Cabrera, P Redondo • Dec 2007 • Venous Ulcers.

Honors[3][edit]

  • Honorary member of the International Union of Angiology.
  • Honorary member of the Pan-American Society of Phlebology and Lymphology.
  • Honorary Mention in the "Cid Dos Santo - Boehringer Mannheim" Award of the University of Coimbra (Portugal) for his study "La voie anastomotique arterielle mamaire interne - epigastrique. Étude fonctional et valoration de son importance dans la pathologie du secteur aorto - iliaque".

Also see[edit]

References[edit]

  1. Olagüe, Guillermo. (2001). Sobre sólida roca fundada : ciento veinte años de labor docente, asistencial e investigadora en la Facultad de Medicina de Granada, 1857-1976. Granada: Universidad de Granada. ISBN 84-338-2764-2. OCLC 48639780. Search this book on
  2. "Andalusian Society of Angiology and Vascular Surgery - History". Unknown parameter |url-status= ignored (help)
  3. 3.0 3.1 "Dr. Juan Cabrera - Researchgate profile". Unknown parameter |url-status= ignored (help)
  4. Gobin, JP; Benigni, JP (2006). "Précisions sur l´origine de la Mousse Sclerosant". Phlébologie (59, 2): 119. Unknown parameter |url-status= ignored (help)
  5. Thompson, M. M. (2008). Endovascular intervention for vascular disease : principles and practice. Informa Healthcare. pp. 527–530, 533. ISBN 978-1-4200-2095-3. OCLC 191869269. Search this book on
    Earnshaw, J. J.; Murie, John A.; Joint Vascular Research Group. (2007). The evidence for vascular surgery. TFM. p. 199. ISBN 978-1-903378-45-8. OCLC 71165310. Search this book on
    Almeida, Jose I. (27 July 2018). Atlas of endovascular venous surgery. pp. 186–193. ISBN 978-0-323-56852-4. OCLC 1048935140. Search this book on
    Alam, Murad; Silapunt, Sirunya (2011). Treatment of leg veins. Saunders/Elsevier. p. 45, 57, 58. ISBN 978-1-4377-3617-5. OCLC 759158658. Search this book on
    Sadick, Neil S.; Khilnani, Neil; Morrison, Nick (2013). Practical approach to the management and treatment of venous disorders. Springer. p. 3. ISBN 978-1-4471-2891-5. OCLC 812017693. Search this book on
    Thompson, Matthew M; Fitridge, Robert; Boyle, Jon; Thompson, Matt; Brohi, Karim; Hinchliffe, Robert J; Cheshire, Nick; Naylor, A. Ross; Loftus, Ian; Davies, Alun H, eds. (August 2016). Oxford Textbook of Vascular Surgery. Oxford University Press. p. 690. doi:10.1093/med/9780199658220.001.0001. ISBN 978-0-19-965822-0. Search this book on
    Vasudevan, Biju; Chatterjee, Manas; K., Shilpa (26 April 2018). Procedural dermatosurgery : a step by step approach. p. 460. ISBN 978-93-5270-212-1. OCLC 1049824758. Search this book on
    Venkataram, Mysore; Association of Cutaneous Surgeons of India (17 July 2017). ACS(I) textbook of cutaneous and aesthetic surgery. pp. 460, 467. ISBN 978-93-5270-033-2. OCLC 1063430908. Search this book on
  6. 6.0 6.1 Goldman, Mitchel P.; Guex, Jean-Jerome (2016). Sclerotherapy : treatment of varicose and telangiectatic leg veins. Elsevier Science Health Science. pp. 171, 251, 255. ISBN 978-0-323-37727-0. OCLC 959274899. Search this book on
  7. Lee, Byung-Boong; Gloviczki, Peter; Blei, Francine (27 November 2019). Vascular malformations : advances and controversies in contemporary management. p. 171. ISBN 978-0-367-25534-3. OCLC 1112138760. Search this book on
  8. EP patent 0656203, Juan Cabrera Garrido & Juan Cabrera Garcia-Olmedo, "Injectable microfoam containing a sclerosing agent", published 1995-06-07, assigned to BTG International Ltd 
  9. "FDA Approves Varithena". Drugs.com. 26 November 2013. Retrieved 4 August 2020.
  10. "Varithena".
    Carugo, Dario; Ankrett, Dyan N.; Zhao, Xuefeng; Zhang, Xunli; Hill, Martyn; O'Byrne, Vincent; Hoad, James; Arif, Mehreen; Wright, David D. I. (May 2016). "Benefits of polidocanol endovenous microfoam (Varithena®) compared with physician-compounded foams". Phlebology. 31 (4): 283–295. doi:10.1177/0268355515589063. ISSN 1758-1125. PMC 4838175. PMID 26036246.
    Star, Phoebe; Connor, David E; Parsi, Kurosh (April 2018). "Novel developments in foam sclerotherapy: Focus on Varithena® (polidocanol endovenous microfoam) in the management of varicose veins". Phlebology: The Journal of Venous Disease. 33 (3): 150–162. doi:10.1177/0268355516687864. ISSN 0268-3555. PMID 28166694. Unknown parameter |s2cid= ignored (help)
    Gibson, Kathleen; Kabnick, Lowell; Varithena 013 Investigator Group (April 2017). "A multicenter, randomized, placebo-controlled study to evaluate the efficacy and safety of Varithena® (polidocanol endovenous microfoam 1%) for symptomatic, visible varicose veins with saphenofemoral junction incompetence". Phlebology. 32 (3): 185–193. doi:10.1177/0268355516635386. ISSN 1758-1125. PMC 5405826. PMID 27013511.
    Todd, Kenneth L.; Wright, D. I.; VANISH-2 Investigator Group (October 2014). "The VANISH-2 study: a randomized, blinded, multicenter study to evaluate the efficacy and safety of polidocanol endovenous microfoam 0.5% and 1.0% compared with placebo for the treatment of saphenofemoral junction incompetence". Phlebology. 29 (9): 608–618. doi:10.1177/0268355513497709. ISSN 1758-1125. PMID 23864535. Unknown parameter |s2cid= ignored (help)
    Eckmann, David M. (December 2009). "Polidocanol for endovenous microfoam sclerosant therapy". Expert Opinion on Investigational Drugs. 18 (12): 1919–1927. doi:10.1517/13543780903376163. ISSN 1744-7658. PMC 2787977. PMID 19912070.
  11. Cabrera, J.; J. Cabrera, Jr; García-Olmedo, M.A. "Treatment of Varicose Long Saphenous Veins with Sclerosant in Microfoam Form: Long-Term Outcomes:". Phlebology. doi:10.1177/026835550001500103.
  12. J, Cabrera; J, Cabrera; Ma, Garcia-Olmedo (Jan 2001). "Sclerosants in microfoam. A new approach in angiology". International angiology : a journal of the International Union of Angiology. PMID 11782699. Unknown parameter |url-status= ignored (help)
  13. Cabrera, Juan (2003-11-01). "Treatment of Venous Malformations With Sclerosant in Microfoam Form". Archives of Dermatology. 139 (11): 1409. doi:10.1001/archderm.139.11.1409. ISSN 0003-987X.
  14. J, Cabrera; P, Redondo (2004). "[Sclerosing treatment of vascular malformations]". Anales del sistema sanitario de Navarra. PMID 15148517. Unknown parameter |url-status= ignored (help)
  15. J, Cabrera; P, Redondo; A, Becerra; C, Garrido; J, Cabrera; Ma, García-Olmedo; A, Sierra; P, Lloret; Ma, Martínez-González (Jun 2004). "Ultrasound-guided injection of polidocanol microfoam in the management of venous leg ulcers". Archives of dermatology. PMID 15210456. Unknown parameter |url-status= ignored (help)
  16. Cabrera, Juan; Redondo, Pedro (Dec 2007), "Foam treatment of venous leg ulcers: the initial experience", Venous Ulcers, Elsevier, pp. 199–213, doi:10.1016/b978-012373565-2.50019-1, ISBN 978-0-12-373565-2

External links[edit]


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